| http://purl.uniprot.org/citations/9364936 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9364936 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9364936 | http://www.w3.org/2000/01/rdf-schema#comment | "Chemokines mediate their chemotactic, proinflammatory effects by binding to and activating a variety of specific receptors belonging to the G protein-coupled superfamily of seven-transmembrane serpentine receptors. We report the cloning, chromosomal localization, expression, and ligand binding of a novel CC chemokine receptor, CCR10. CCR10 is expressed primarily in placenta and fetal liver, and binds two of the CC chemokines, monocyte chemoattractant protein (MCP)-1 and MCP-3, with highest affinity. The KD for MCP-3 binding was 1 nM, and MCP-1 competed for MCP-3 binding with an IC50 of 1.2 nM. The CC chemokines MCP-4 and RANTES competed for MCP-3 binding with IC50 values of 7.5 and 5.4 nM, respectively. The chromosomal location of CCR10 was determined to coincide with the CC chemokine receptor cluster on chromosome 3 (3p21.31-3p21.32). These results indicate that CCR10 is a novel CC chemokine receptor with a unique expression pattern that would be consistent with a role in placental immunity or hematopoiesis."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.org/dc/terms/identifier | "doi:10.1089/dna.1997.16.1249"xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.org/dc/terms/identifier | "doi:10.1089/dna.1997.16.1249"xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/author | "Martin S.K."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/author | "Martin S.K."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/author | "Steiner D.F."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/author | "Steiner D.F."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/author | "Bonini J.A."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/author | "Bonini J.A."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/author | "Dralyuk F."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/author | "Dralyuk F."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/author | "Philipson L.H."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/author | "Philipson L.H."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/author | "Roe M.W."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/author | "Roe M.W."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/name | "DNA Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/name | "DNA Cell Biol."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/pages | "1249-1256"xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/pages | "1249-1256"xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/title | "Cloning, expression, and chromosomal mapping of a novel human CC-chemokine receptor (CCR10) that displays high-affinity binding for MCP-1 and MCP-3."xsd:string |
| http://purl.uniprot.org/citations/9364936 | http://purl.uniprot.org/core/title | "Cloning, expression, and chromosomal mapping of a novel human CC-chemokine receptor (CCR10) that displays high-affinity binding for MCP-1 and MCP-3."xsd:string |