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http://purl.uniprot.org/citations/9371841http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9371841http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9371841http://www.w3.org/2000/01/rdf-schema#comment"The mesencephalic dopaminergic (mesDA) system regulates behavior and movement control and has been implicated in psychiatric and affective disorders. We have identified a bicoid-related homeobox gene, Ptx3, a member of the Ptx-subfamily, that is uniquely expressed in these neurons. Its expression starting at E11.5 in the developing mouse midbrain correlates with the appearance of mesDA neurons. The number of Ptx3-expressing neurons is reduced in Parkinson patients, and these neurons are absent from 6-hydroxydopamine-lesioned rats, an animal model for this disease. Thus, Ptx3 is a unique transcription factor marking the mesDA neurons at the exclusion of other dopaminergic neurons, and it may be involved in developmental determination of this neuronal lineage."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.org/dc/terms/identifier"doi:10.1073/pnas.94.24.13305"xsd:string
http://purl.uniprot.org/citations/9371841http://purl.org/dc/terms/identifier"doi:10.1073/pnas.94.24.13305"xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Drouin J."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Drouin J."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Lanctot C."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Lanctot C."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Cox J.J."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Cox J.J."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Burbach J.P.H."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Burbach J.P.H."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Smidt M.P."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Smidt M.P."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Tremblay J.T."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Tremblay J.T."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Wolterink G."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"Wolterink G."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"van Shaick H.S.A."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"van Shaick H.S.A."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"van der Kleij A.A.M."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/author"van der Kleij A.A.M."xsd:string
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9371841http://purl.uniprot.org/core/date"1997"xsd:gYear