RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/9373176http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9373176http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9373176http://www.w3.org/2000/01/rdf-schema#comment"cDNA cloning of glutamate transporter GLT-1 from mouse brain and liver has revealed that 5'-ends of the messages are different between brain and liver. In addition, one of the GLT-1 cDNAs isolated from liver has been found to possess a 3'-end different from those of the others. Reverse transcription polymerase chain reaction (RT-PCR) amplification using primers specific for altered 5'-ends has confirmed that brain and liver messages possess their own specific 5'-ends. Both of the two 3'-ends have been demonstrated by RT-PCR to be present not only in liver but also in brain, indicating both brain and liver GLT-1 possess two types of 3'-ends. Although functional properties are not changed by the alteration of N-termini and C-termini when expressed in Xenopus laevis oocytes, co-expression of two liver type GLT-1 with different C-termini (mGLT-1A and mGLT-1B) has been found to result in the increase in Vmax of transport without changing Km. These results suggest the tissue specific alternative splicing at 5'-ends of GLT-1 messages and the interesting association of spliced variants with different C-termini."xsd:string
http://purl.uniprot.org/citations/9373176http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(97)01232-5"xsd:string
http://purl.uniprot.org/citations/9373176http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(97)01232-5"xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/author"Endou H."xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/author"Endou H."xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/author"Kanai Y."xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/author"Kanai Y."xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/author"Utsunomiya-Tate N."xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/author"Utsunomiya-Tate N."xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/pages"312-316"xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/pages"312-316"xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/title"Tissue specific variants of glutamate transporter GLT-1."xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/title"Tissue specific variants of glutamate transporter GLT-1."xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/volume"416"xsd:string
http://purl.uniprot.org/citations/9373176http://purl.uniprot.org/core/volume"416"xsd:string
http://purl.uniprot.org/citations/9373176http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9373176
http://purl.uniprot.org/citations/9373176http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9373176
http://purl.uniprot.org/citations/9373176http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9373176
http://purl.uniprot.org/citations/9373176http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9373176