| http://purl.uniprot.org/citations/9405671 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9405671 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9405671 | http://www.w3.org/2000/01/rdf-schema#comment | "Wiskott-Aldrich syndrome (WAS) is an X-linked immunodeficiency caused by mutations that affect the WAS protein (WASP) and characterized by cytoskeletal abnormalities in hematopoietic cells. By using the yeast two-hybrid system we have identified a proline-rich WASP-interacting protein (WIP), which coimmunoprecipitated with WASP from lymphocytes. WIP binds to WASP at a site distinct from the Cdc42 binding site and has actin as well as profilin binding motifs. Expression of WIP in human B cells, but not of a WIP truncation mutant that lacks the actin binding motif, increased polymerized actin content and induced the appearance of actin-containing cerebriform projections on the cell surface. These results suggest that WIP plays a role in cortical actin assembly that may be important for lymphocyte function."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.94.26.14671"xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.94.26.14671"xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/author | "Hartwig J.H."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/author | "Hartwig J.H."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/author | "Anton I.M."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/author | "Anton I.M."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/author | "Geha R.S."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/author | "Geha R.S."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/author | "Ramesh N."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/author | "Ramesh N."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/pages | "14671-14676"xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/pages | "14671-14676"xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/title | "WIP, a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/title | "WIP, a protein associated with Wiskott-Aldrich syndrome protein, induces actin polymerization and redistribution in lymphoid cells."xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/volume | "94"xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://purl.uniprot.org/core/volume | "94"xsd:string |
| http://purl.uniprot.org/citations/9405671 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9405671 |
| http://purl.uniprot.org/citations/9405671 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9405671 |