http://purl.uniprot.org/citations/9413987 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9413987 | http://www.w3.org/2000/01/rdf-schema#comment | "The steroid hormone ecdysone directs Drosophila metamorphosis via three heterodimeric receptors that differ according to which of three ecdysone receptor isoforms encoded by the EcR gene (EcR-A, EcR-B1, or EcR-B2) is activated by the orphan nuclear receptor USP. We have identified and molecularly mapped two classes of EcR mutations: those specific to EcR-B1 that uncouple metamorphosis, and embryonic-lethal mutations that map to common sequences encoding the DNA- and ligand-binding domains. In the larval salivary gland, loss of EcR-B1 results in loss of activation of ecdysone-induced genes. Comparable transgenic expression of EcR-B1, EcR-B2, and EcR-A in these mutant glands results, respectively, in full, partial, and no repair of that loss."xsd:string |
http://purl.uniprot.org/citations/9413987 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)80466-3"xsd:string |
http://purl.uniprot.org/citations/9413987 | http://purl.uniprot.org/core/author | "Hogness D.S."xsd:string |
http://purl.uniprot.org/citations/9413987 | http://purl.uniprot.org/core/author | "Ganetzky B."xsd:string |
http://purl.uniprot.org/citations/9413987 | http://purl.uniprot.org/core/author | "Talbot W.S."xsd:string |
http://purl.uniprot.org/citations/9413987 | http://purl.uniprot.org/core/author | "Bender M."xsd:string |
http://purl.uniprot.org/citations/9413987 | http://purl.uniprot.org/core/author | "Imam F.B."xsd:string |
http://purl.uniprot.org/citations/9413987 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9413987 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/9413987 | http://purl.uniprot.org/core/pages | "777-788"xsd:string |
http://purl.uniprot.org/citations/9413987 | http://purl.uniprot.org/core/title | "Drosophila ecdysone receptor mutations reveal functional differences among receptor isoforms."xsd:string |
http://purl.uniprot.org/citations/9413987 | http://purl.uniprot.org/core/volume | "91"xsd:string |
http://purl.uniprot.org/citations/9413987 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9413987 |
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