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http://purl.uniprot.org/citations/9413987http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9413987http://www.w3.org/2000/01/rdf-schema#comment"The steroid hormone ecdysone directs Drosophila metamorphosis via three heterodimeric receptors that differ according to which of three ecdysone receptor isoforms encoded by the EcR gene (EcR-A, EcR-B1, or EcR-B2) is activated by the orphan nuclear receptor USP. We have identified and molecularly mapped two classes of EcR mutations: those specific to EcR-B1 that uncouple metamorphosis, and embryonic-lethal mutations that map to common sequences encoding the DNA- and ligand-binding domains. In the larval salivary gland, loss of EcR-B1 results in loss of activation of ecdysone-induced genes. Comparable transgenic expression of EcR-B1, EcR-B2, and EcR-A in these mutant glands results, respectively, in full, partial, and no repair of that loss."xsd:string
http://purl.uniprot.org/citations/9413987http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(00)80466-3"xsd:string
http://purl.uniprot.org/citations/9413987http://purl.uniprot.org/core/author"Hogness D.S."xsd:string
http://purl.uniprot.org/citations/9413987http://purl.uniprot.org/core/author"Ganetzky B."xsd:string
http://purl.uniprot.org/citations/9413987http://purl.uniprot.org/core/author"Talbot W.S."xsd:string
http://purl.uniprot.org/citations/9413987http://purl.uniprot.org/core/author"Bender M."xsd:string
http://purl.uniprot.org/citations/9413987http://purl.uniprot.org/core/author"Imam F.B."xsd:string
http://purl.uniprot.org/citations/9413987http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9413987http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/9413987http://purl.uniprot.org/core/pages"777-788"xsd:string
http://purl.uniprot.org/citations/9413987http://purl.uniprot.org/core/title"Drosophila ecdysone receptor mutations reveal functional differences among receptor isoforms."xsd:string
http://purl.uniprot.org/citations/9413987http://purl.uniprot.org/core/volume"91"xsd:string
http://purl.uniprot.org/citations/9413987http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9413987
http://purl.uniprot.org/citations/9413987http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9413987
http://purl.uniprot.org/uniprot/#_E1JGY2-mappedCitation-9413987http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9413987
http://purl.uniprot.org/uniprot/#_A4UZ51-mappedCitation-9413987http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9413987
http://purl.uniprot.org/uniprot/#_A0A0S0WIG6-mappedCitation-9413987http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9413987
http://purl.uniprot.org/uniprot/#_A0A6H2EEH5-mappedCitation-9413987http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9413987
http://purl.uniprot.org/uniprot/#_D8FT05-mappedCitation-9413987http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9413987
http://purl.uniprot.org/uniprot/#_M9MSK2-mappedCitation-9413987http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9413987
http://purl.uniprot.org/uniprot/#_M9MSM6-mappedCitation-9413987http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9413987
http://purl.uniprot.org/uniprot/#_P20105-mappedCitation-9413987http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9413987
http://purl.uniprot.org/uniprot/#_E1JJB2-mappedCitation-9413987http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9413987
http://purl.uniprot.org/uniprot/#_E2QCT0-mappedCitation-9413987http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9413987