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http://purl.uniprot.org/citations/9428732http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9428732http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9428732http://www.w3.org/2000/01/rdf-schema#comment"PSD-95/SAP90, which binds to the C-terminus of NMDA receptor and Shaker-type potassium channel, is one of the major postsynaptic density proteins. Recently, novel classes of proteins interacting with the guanylate kinase domain of PSD-95 have been identified, guanylate kinase-associated protein (GKAP) and SAP90/PSD-95-associated proteins (SAPAPs). Here we report the isolation of new isoforms of PSD-95 binding protein (GKAP/SAPAP1) using the yeast two-hybrid system. The isolated protein directly interacts with the guanylate kinase domain of PSD-95. Northern blot analyses revealed that the expression of these isoforms containing distinct N-terminal sequences is differentially regulated during brain development. The present findings suggest that each isoform of the PSD-95 binding protein is differentially expressed in a development-dependent manner and may be involved in the complex formation of PSD-95 and channel/receptors at the postsynaptic density."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(97)01399-9"xsd:string
http://purl.uniprot.org/citations/9428732http://purl.org/dc/terms/identifier"doi:10.1016/s0014-5793(97)01399-9"xsd:string
http://purl.uniprot.org/citations/9428732http://purl.org/dc/terms/identifier"doi:10.1016/S0014-5793(97)01399-9"xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/author"Sun J."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/author"Sun J."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/author"Sobue K."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/author"Sobue K."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/author"Takamiya K."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/author"Takamiya K."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/author"Kitabatake A."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/author"Kitabatake A."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/author"Kawashima N."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/author"Kawashima N."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/name"FEBS Lett."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/pages"301-304"xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/pages"301-304"xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/title"Differential expression of isoforms of PSD-95 binding protein (GKAP/SAPAP1) during rat brain development."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/title"Differential expression of isoforms of PSD-95 binding protein (GKAP/SAPAP1) during rat brain development."xsd:string
http://purl.uniprot.org/citations/9428732http://purl.uniprot.org/core/volume"418"xsd:string