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http://purl.uniprot.org/citations/9434190http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9434190http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9434190http://www.w3.org/2000/01/rdf-schema#comment"HRS/SRp40/SFRS5 (HRS) is an SR (serine-arginine-rich) protein which regulates both alternative splicing and basal splicing. HRS mRNA contains several transcripts, including HRS-SF and HRS-LF which have different temporal patterns of expression in proliferating liver. As previously reported, HRS-SF mRNA encodes the SR splicing factor. However, the identity of HRS-LF remained unknown. Here, we cloned and characterized the mouse HRS gene, partial human HRS gene, and several cDNAs derived from HRS-LF mRNA. The mouse HRS gene spans 5050 bp and contains eight exons and seven introns. HRS-LF mRNA contains a 1.2 kb insert within the SF mRNA with stop codons in all three reading frames. A comparison of HRS-LF and the HRS gene revealed that HRS-LF mRNA is an intron-retaining product which contains intron 5. At most, HRS-LF encodes a truncated HRS protein with one RNA binding domain. Interestingly, intron 5 demonstrates 90% identity between the mouse and human HRS genes, implying that intron 5 might play an important role in regulating HRS gene splicing or expression."xsd:string
http://purl.uniprot.org/citations/9434190http://purl.org/dc/terms/identifier"doi:10.1016/s0378-1119(97)00552-0"xsd:string
http://purl.uniprot.org/citations/9434190http://purl.org/dc/terms/identifier"doi:10.1016/s0378-1119(97)00552-0"xsd:string
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/author"Du K."xsd:string
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/author"Du K."xsd:string
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/author"Taub R."xsd:string
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/author"Taub R."xsd:string
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/pages"243-249"xsd:string
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/pages"243-249"xsd:string
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/title"Alternative splicing and structure of the human and mouse SFRS5/HRS/SRp40 genes."xsd:string
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/title"Alternative splicing and structure of the human and mouse SFRS5/HRS/SRp40 genes."xsd:string
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/volume"204"xsd:string
http://purl.uniprot.org/citations/9434190http://purl.uniprot.org/core/volume"204"xsd:string
http://purl.uniprot.org/citations/9434190http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9434190
http://purl.uniprot.org/citations/9434190http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9434190
http://purl.uniprot.org/citations/9434190http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9434190
http://purl.uniprot.org/citations/9434190http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9434190
http://purl.uniprot.org/uniprot/O35326http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/9434190
http://purl.uniprot.org/embl-cds/AAB71864.1http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/9434190