| http://purl.uniprot.org/citations/9435235 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9435235 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9435235 | http://www.w3.org/2000/01/rdf-schema#comment | "Nuclear import of proteins containing a nuclear localization signal (NLS) is dependent on the presence of a cytoplasmic NLS receptor, the GTPase Ran, and p10/ NTF2. The NLS receptor is a heterodimeric proteins consisting of subunits of approximately 60 and 97 kDa, which have been termed importin alpha/beta, karyopherin alpha/beta, or PTAC 58/ 97. Members of the 60-kDa/importin alpha subunit family directly bind to the NLS motif and have been shown to function as adaptors that tether NLS-containing proteins to the p97/ importin beta subunit and to the downstream transport machinery. Herein we report the identification and characterization of hSRP1 gamma, a human importin alpha homologue. The hSRP1 gamma protein is around 45% identical to the previously identified human importin alpha homologues hSRP1 alpha/Rch1 and NPI/ hSRP1. hSRP1 gamma can form a complex with importin beta and is able to mediate import of a BSA-NLS substrate in an in vitro nuclear import system. Interestingly, hSRP1 gamma shows a very selective expression pattern and is most abundantly expressed in skeletal muscle, representing more than 1% of the total protein in this tissue. A potential role for hSRP1 gamma in tissue-specific transport events is discussed."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.95.2.582"xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.95.2.582"xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/author | "Lamond A.I."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/author | "Lamond A.I."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/author | "Nachury M.V."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/author | "Nachury M.V."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/author | "Weis K."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/author | "Weis K."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/author | "Ryder U.W."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/author | "Ryder U.W."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/name | "Proc. Natl. Acad. Sci. U.S.A."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/pages | "582-587"xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/pages | "582-587"xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/title | "Cloning and characterization of hSRP1 gamma, a tissue-specific nuclear transport factor."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/title | "Cloning and characterization of hSRP1 gamma, a tissue-specific nuclear transport factor."xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/volume | "95"xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://purl.uniprot.org/core/volume | "95"xsd:string |
| http://purl.uniprot.org/citations/9435235 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9435235 |
| http://purl.uniprot.org/citations/9435235 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9435235 |