| http://purl.uniprot.org/citations/9439675 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9439675 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9439675 | http://www.w3.org/2000/01/rdf-schema#comment | "In the present study, we searched for genetic alterations of the entire coding region of PTEN/MMAC1, a recently isolated candidate tumor suppressor gene, in 178 specimens from Japanese patients with various malignant tumors by the polymerase chain reaction-single strand conformation polymorphism method. The samples consisted of 11 glioblastoma multiformes (GBMs), 14 astrocytomas, 47 breast cancers, 25 non-small cell lung cancers, 9 small cell lung cancers, 8 pancreatic cancers, 24 renal cell carcinomas, 20 ovarian cancers, and 20 metastatic lung tumors from various organs. Only one somatic frameshift mutation at codon 319 was observed in one (9%) of eleven GBMs. Our results suggest that mutation of the PTEN/MMAC1 gene does not play a major role in carcinogenesis, at least in the tumor types from Japanese patients analyzed in this study."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1349-7006.1997.tb00324.x"xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Ono T."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Ono T."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Sato M."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Sato M."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Suzuki A."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Suzuki A."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Fujimura S."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Fujimura S."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Yamakawa H."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Yamakawa H."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Horii A."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Horii A."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Ohuchi N."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Ohuchi N."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Sakurada A."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Sakurada A."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Orikasa K."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Orikasa K."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Uyeno S."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/author | "Uyeno S."xsd:string |
| http://purl.uniprot.org/citations/9439675 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |