http://purl.uniprot.org/citations/9442388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9442388 | http://www.w3.org/2000/01/rdf-schema#comment | "In order to elucidate the role of NF-ATp, one of the most prominent members of family of NF-AT transcription factors in peripheral T lymphocytes, in T cell activation and differentiation we created NF-ATp-deficient mice by gene targeting. Such NF-ATp-/-mice are born and appear to develop a normal immune system. Apart from clear-cut defects in the synthesis of mRNAs for Th2-type lymphokines, such as IL-4, IL-5, IL-10 and IL-13, in primary and secondary stimulations of spleen cells in vitro, of a distinct impaired deletion of V beta 11+/CD4+ T lymphocytes from these mice was detected after superantigen injection. Moreover, NF-ATp-/-mice older than 6 weeks show an 2-5 fold increase in number of lymphocytes. This is correlated with an increased expression of activation markers CD44 and CD69 and decreased expression of CD62."xsd:string |
http://purl.uniprot.org/citations/9442388 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0171-2985(97)80037-x"xsd:string |
http://purl.uniprot.org/citations/9442388 | http://purl.uniprot.org/core/author | "Jankevics E."xsd:string |
http://purl.uniprot.org/citations/9442388 | http://purl.uniprot.org/core/author | "Schuh K."xsd:string |
http://purl.uniprot.org/citations/9442388 | http://purl.uniprot.org/core/author | "Schimpl A."xsd:string |
http://purl.uniprot.org/citations/9442388 | http://purl.uniprot.org/core/author | "Serfling E."xsd:string |
http://purl.uniprot.org/citations/9442388 | http://purl.uniprot.org/core/author | "Siebelt F."xsd:string |
http://purl.uniprot.org/citations/9442388 | http://purl.uniprot.org/core/author | "Heyer J."xsd:string |
http://purl.uniprot.org/citations/9442388 | http://purl.uniprot.org/core/author | "Kneitz B."xsd:string |
http://purl.uniprot.org/citations/9442388 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
http://purl.uniprot.org/citations/9442388 | http://purl.uniprot.org/core/name | "Immunobiology"xsd:string |
http://purl.uniprot.org/citations/9442388 | http://purl.uniprot.org/core/pages | "162-169"xsd:string |
http://purl.uniprot.org/citations/9442388 | http://purl.uniprot.org/core/title | "Inefficient termination of antigen responses in NF-ATp-deficient mice."xsd:string |
http://purl.uniprot.org/citations/9442388 | http://purl.uniprot.org/core/volume | "198"xsd:string |
http://purl.uniprot.org/citations/9442388 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9442388 |
http://purl.uniprot.org/citations/9442388 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9442388 |
http://purl.uniprot.org/uniprot/#_A2AQC8-mappedCitation-9442388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9442388 |
http://purl.uniprot.org/uniprot/#_B5B2P6-mappedCitation-9442388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9442388 |
http://purl.uniprot.org/uniprot/#_B5B2P7-mappedCitation-9442388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9442388 |
http://purl.uniprot.org/uniprot/#_B5B2P8-mappedCitation-9442388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9442388 |
http://purl.uniprot.org/uniprot/#_B5B2Q2-mappedCitation-9442388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9442388 |
http://purl.uniprot.org/uniprot/#_B5B2Q4-mappedCitation-9442388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9442388 |
http://purl.uniprot.org/uniprot/#_B5B2Q6-mappedCitation-9442388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9442388 |
http://purl.uniprot.org/uniprot/#_B5B2Q8-mappedCitation-9442388 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9442388 |