| http://purl.uniprot.org/citations/9446799 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9446799 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9446799 | http://www.w3.org/2000/01/rdf-schema#comment | "SR-protein-specific kinase 1 (SRPK1) is first identified as a specific kinase for SR splicing factors. By RT-PCR of a conserved kinase domain, novel SR-protein-specific kinase clones were isolated from mouse brain. The cloned cDNAs encode a 106 kDa protein (648 amino acids, 92% identical to human SRPK1) and a 120 kDa protein (681 amino acids, 58% identical to human SRPK1). Therefore, they were designated mSRPK1 and mSRPK2, respectively. Northern blotting revealed the ubiquitous expression of mSRPK1 in all tissues examined and the tissue-specific expression of mSRPK2 in testis, lung, and brain. Both kinases phosphorylated SF2/ASF, a member of SR proteins in vitro and the phosphopeptide mappings were identical, indicating that these kinases phosphorylate the same site of SF2/ASF. Overexpression of mSRPK2 caused disassembly of cotransfected SF2/ASF and endogenous SC35. Our results indicate that SRPK family members may regulate the disassembly of the SR proteins in a tissue-specific manner."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1997.7913"xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1997.7913"xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/author | "Hagiwara M."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/author | "Hagiwara M."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/author | "Wakabayashi T."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/author | "Wakabayashi T."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/author | "Onogi H."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/author | "Onogi H."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/author | "Kuroyanagi N."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/author | "Kuroyanagi N."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/pages | "357-364"xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/pages | "357-364"xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/title | "Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/title | "Novel SR-protein-specific kinase, SRPK2, disassembles nuclear speckles."xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/volume | "242"xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://purl.uniprot.org/core/volume | "242"xsd:string |
| http://purl.uniprot.org/citations/9446799 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9446799 |
| http://purl.uniprot.org/citations/9446799 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9446799 |