| http://purl.uniprot.org/citations/9450550 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9450550 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9450550 | http://www.w3.org/2000/01/rdf-schema#comment | "We have purified a form of protein phosphatase 1 (PP1) from HeLa cell nuclei, in which the phosphatase is complexed to a regulatory subunit termed p99. We report here the cloning and characterisation of the p99 component. p99 mRNA is widely expressed in human tissues and immunofluorescence analysis with anti-p99 antibodies showed a punctate nucleoplasmic staining with additional accumulations within the nucleolus. The C-terminus of p99 contains seven RGG RNA-binding motifs, followed by eleven decapeptide repeats containing six or more of the following conserved residues (GHRPHEGPGG), and finally a putative zinc finger domain. Recombinant p99 suppresses the phosphorylase phosphatase activity of PP1 by > 90% and the canonical PP1-binding motif on p99 (residues 396-401) is unusual in that the phenylalanine residue is replaced by tryptophan."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(97)01485-3"xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(97)01485-3"xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/author | "Morrice N.A."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/author | "Morrice N.A."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/author | "Cohen P."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/author | "Cohen P."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/author | "Lamond A.I."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/author | "Lamond A.I."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/author | "Trinkle-Mulcahy L."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/author | "Trinkle-Mulcahy L."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/author | "Lyon C.E."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/author | "Lyon C.E."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/author | "Kreivi J.P."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/author | "Kreivi J.P."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/pages | "57-62"xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/pages | "57-62"xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/title | "Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity."xsd:string |
| http://purl.uniprot.org/citations/9450550 | http://purl.uniprot.org/core/title | "Purification and characterisation of p99, a nuclear modulator of protein phosphatase 1 activity."xsd:string |