| http://purl.uniprot.org/citations/9450989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9450989 | http://www.w3.org/2000/01/rdf-schema#comment | "The uptake step of receptor-mediated endocytosis in yeast is dependent on the calcium binding protein calmodulin (Cmd1p). In order to understand the role that Cmd1p plays, a search was carried out for possible targets among the genes required for the internalization process. Co-immunoprecipitation, two-hybrid and overlay assays demonstrated that Cmd1p interacts with Myo5p, a type I unconventional myosin. Analysis of the endocytic phenotype and the Cmd1p-Myo5p interaction in thermosensitive cmd1 mutants indicated that the Cmd1p-Myo5p interaction is required for endocytosis in vivo. However, the Cmd1p-Myo5p interaction requirement was partially overcome by deleting the calmodulin binding sites (IQ motifs) from Myo5p, suggesting that these motifs inhibit Myo5p function. Additionally, genetic and biochemical evidence obtained with a collection of cmd1 mutant alleles strongly suggests that Cmd1p plays an additional role in the internalization step of receptor-mediated endocytosis in yeast."xsd:string |
| http://purl.uniprot.org/citations/9450989 | http://purl.org/dc/terms/identifier | "doi:10.1093/emboj/17.3.635"xsd:string |
| http://purl.uniprot.org/citations/9450989 | http://purl.uniprot.org/core/author | "Riezman H."xsd:string |
| http://purl.uniprot.org/citations/9450989 | http://purl.uniprot.org/core/author | "Geli M.I."xsd:string |
| http://purl.uniprot.org/citations/9450989 | http://purl.uniprot.org/core/author | "Wesp A."xsd:string |
| http://purl.uniprot.org/citations/9450989 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9450989 | http://purl.uniprot.org/core/name | "EMBO J"xsd:string |
| http://purl.uniprot.org/citations/9450989 | http://purl.uniprot.org/core/pages | "635-647"xsd:string |
| http://purl.uniprot.org/citations/9450989 | http://purl.uniprot.org/core/title | "Distinct functions of calmodulin are required for the uptake step of receptor-mediated endocytosis in yeast: the type I myosin Myo5p is one of the calmodulin targets."xsd:string |
| http://purl.uniprot.org/citations/9450989 | http://purl.uniprot.org/core/volume | "17"xsd:string |
| http://purl.uniprot.org/citations/9450989 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9450989 |
| http://purl.uniprot.org/citations/9450989 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9450989 |
| http://purl.uniprot.org/uniprot/P06787#attribution-62E29148201F0031785DB992EBBCC6EF | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/9450989 |
| http://purl.uniprot.org/uniprot/#_P06787-mappedCitation-9450989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9450989 |
| http://purl.uniprot.org/uniprot/#_Q04439-mappedCitation-9450989 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9450989 |
| http://purl.uniprot.org/uniprot/P06787 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/9450989 |
| http://purl.uniprot.org/uniprot/Q04439 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/9450989 |