| http://purl.uniprot.org/citations/9453234 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9453234 | http://www.w3.org/2000/01/rdf-schema#comment | "In mice lacking the nociceptin (or orphanin FQ) receptor gene, when 10 mg/kg of morphine was subcutaneously given, a potent analgesia in the tail pinch test was observed. The analgesic effect of morphine was equivalent among wild-type, heterozygous and homozygous mutant mice. When morphine was given to such mice in a dose of 10 mg/kg once per day for 5 days, wild-type and heterozygous mice showed marked tolerance or reduction in the morphine analgesia on the 5th day, while homozygous mice showed only 50% reduction in the peripheral analgesia of morphine. These findings suggest that nociceptin or its receptor plays important roles in the in vivo mechanism for the development of morphine tolerance."xsd:string |
| http://purl.uniprot.org/citations/9453234 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0304-3940(97)00832-x"xsd:string |
| http://purl.uniprot.org/citations/9453234 | http://purl.uniprot.org/core/author | "Inoue M."xsd:string |
| http://purl.uniprot.org/citations/9453234 | http://purl.uniprot.org/core/author | "Yamaguchi T."xsd:string |
| http://purl.uniprot.org/citations/9453234 | http://purl.uniprot.org/core/author | "Takeshima H."xsd:string |
| http://purl.uniprot.org/citations/9453234 | http://purl.uniprot.org/core/author | "Nishi M."xsd:string |
| http://purl.uniprot.org/citations/9453234 | http://purl.uniprot.org/core/author | "Ueda H."xsd:string |
| http://purl.uniprot.org/citations/9453234 | http://purl.uniprot.org/core/author | "Tokuyama S."xsd:string |
| http://purl.uniprot.org/citations/9453234 | http://purl.uniprot.org/core/date | "1997"xsd:gYear |
| http://purl.uniprot.org/citations/9453234 | http://purl.uniprot.org/core/name | "Neurosci Lett"xsd:string |
| http://purl.uniprot.org/citations/9453234 | http://purl.uniprot.org/core/pages | "136-138"xsd:string |
| http://purl.uniprot.org/citations/9453234 | http://purl.uniprot.org/core/title | "Partial loss of tolerance liability to morphine analgesia in mice lacking the nociceptin receptor gene."xsd:string |
| http://purl.uniprot.org/citations/9453234 | http://purl.uniprot.org/core/volume | "237"xsd:string |
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