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http://purl.uniprot.org/citations/9454646http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9454646http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9454646http://www.w3.org/2000/01/rdf-schema#comment"We have cloned and sequenced the gene encoding the translation elongation factor eEF1A from two filamentous fungi, Podospora curvicolla and Sordaria macrospora. These fungi are close relatives of Podospora anserina and also show senescence syndromes. Comparison of the sequences of the deduced proteins with that of P. anserina reveals that the three proteins differ in several positions. Replacement of the P. anserina gene by either of the two exogenous genes does not entail any modification in P. anserina physiology; the longevity of the fungus is not affected. No alteration of in vivo translational accuracy was detected; however, the exogenous proteins nonetheless promoted a modification of the resistance to the aminoglycoside antibiotic paromomycin. These data suggest that optimization of life span between these closely related fungi has likely not been performed during evolution through modifications of eEF1A activity, despite the fact that mutations in this factor can drastically affect longevity."xsd:string
http://purl.uniprot.org/citations/9454646http://purl.org/dc/terms/identifier"doi:10.1006/fgbi.1997.1012"xsd:string
http://purl.uniprot.org/citations/9454646http://purl.org/dc/terms/identifier"doi:10.1006/fgbi.1997.1012"xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/author"Silar P."xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/author"Silar P."xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/author"Rossignol M."xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/author"Rossignol M."xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/author"Gagny B."xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/author"Gagny B."xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/date"1997"xsd:gYear
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/name"Fungal Genet. Biol."xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/name"Fungal Genet. Biol."xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/pages"191-198"xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/pages"191-198"xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/title"Cloning, sequencing, and transgenic expression of Podospora curvicolla and Sordaria macrospora eEF1A genes: relationship between cytosolic translation and longevity in filamentous fungi."xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/title"Cloning, sequencing, and transgenic expression of Podospora curvicolla and Sordaria macrospora eEF1A genes: relationship between cytosolic translation and longevity in filamentous fungi."xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/volume"22"xsd:string
http://purl.uniprot.org/citations/9454646http://purl.uniprot.org/core/volume"22"xsd:string
http://purl.uniprot.org/citations/9454646http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9454646
http://purl.uniprot.org/citations/9454646http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9454646
http://purl.uniprot.org/citations/9454646http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9454646
http://purl.uniprot.org/citations/9454646http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9454646