http://purl.uniprot.org/citations/9464250 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9464250 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9464250 | http://www.w3.org/2000/01/rdf-schema#comment | "To investigate regulation mechanisms of G2/M phase transition, we studied the association of cell cycle progression with p53-dependent p21/waf-1 and cyclinG expression. We used doxorubicin (DOX) and sodium butyrate (NaB) to accumulate p53 protein. DOX treatment resulted in an apparent increase of cells in the G2/M fraction, whereas NaB arrested cells at G1. P53 protein induction in response to DOX accompanied up-regulation of p21/waf-1 and cyclinG expression. However, cyclinG was undetectable in NaB-treated cells. These results implied a putative association between increases in the proportion of cells accumulating in the G2/M fraction and enhanced cyclinG expression. Antisense oligo DNAs (AS) complementary to cyclinG mRNA inhibited the cyclinG protein expression induced by DOX treatment. This inhibition resulted in a marked reduction in the number of cells arrested at G2/M and accumulating at G1. A role for cyclinG in G2/M phase transition control is implied."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1997.8004"xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.org/dc/terms/identifier | "doi:10.1006/bbrc.1997.8004"xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Kato K."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Kato K."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Shimizu A."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Shimizu A."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Nishida J."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Nishida J."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Hachiya T."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Hachiya T."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Kuriaki Y."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Kuriaki Y."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Ueoka Y."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Ueoka Y."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Wake N."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/author | "Wake N."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/name | "Biochem. Biophys. Res. Commun."xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/pages | "529-533"xsd:string |
http://purl.uniprot.org/citations/9464250 | http://purl.uniprot.org/core/pages | "529-533"xsd:string |