| http://purl.uniprot.org/citations/9491996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9491996 | http://www.w3.org/2000/01/rdf-schema#comment | "Patients with major histocompatibility complex class II (MHC-II) deficiency are known to carry mutations in either the RFX complex or the trans-activator CIITA. While the pivotal role of CIITA for MHC-II gene transcription is supported by the essential absence of MHC-II molecules in CIITA-deficient mice, we demonstrate here that RFX5-/-mice retain expression of MHC-II in thymic medulla, mature dendritic cells, and activated B cells. Nevertheless, RFX5-/-mice develop a severe immunodeficiency due to the lack of MHC-II in thymic cortex, failure of positive selection of CD4+ T cells, and absence of MHC-II on resting B cells and resident or IFNgamma-activated macrophages. This differential requirement for CIITA and RFX5 in subsets of antigen-presenting cells may be specific for the mouse; it may, however, also exist in humans without having been noticed so far."xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1074-7613(00)80467-7"xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/author | "Reith W."xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/author | "Clausen B.E."xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/author | "Mach B."xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/author | "Forster I."xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/author | "Rajewsky K."xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/author | "Barras E."xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/author | "Schwenk F."xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/author | "Waldburger J.M."xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/name | "Immunity"xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/pages | "143-155"xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/title | "Residual MHC class II expression on mature dendritic cells and activated B cells in RFX5-deficient mice."xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://purl.uniprot.org/core/volume | "8"xsd:string |
| http://purl.uniprot.org/citations/9491996 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9491996 |
| http://purl.uniprot.org/citations/9491996 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9491996 |
| http://purl.uniprot.org/uniprot/#_A0A068BD71-mappedCitation-9491996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9491996 |
| http://purl.uniprot.org/uniprot/#_A0A068BER6-mappedCitation-9491996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9491996 |
| http://purl.uniprot.org/uniprot/#_A0A1D8M9B3-mappedCitation-9491996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9491996 |
| http://purl.uniprot.org/uniprot/#_A0A1D8M9B5-mappedCitation-9491996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9491996 |
| http://purl.uniprot.org/uniprot/#_D3YVW1-mappedCitation-9491996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9491996 |
| http://purl.uniprot.org/uniprot/#_D3Z0D4-mappedCitation-9491996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9491996 |
| http://purl.uniprot.org/uniprot/#_A0A2R8VHC7-mappedCitation-9491996 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9491996 |