| http://purl.uniprot.org/citations/9527928 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9527928 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9527928 | http://www.w3.org/2000/01/rdf-schema#comment | "The Borna disease virus (BDV) replicates in the nucleus. The viral p40 protein (N), which is found abundantly in the nucleus in BDV-infected cells, may play an important role in virus replication. To analyze the amino acid residues involved in the nuclear targeting of BDV N, a series of eukaryotic expression plasmids encoding deletion mutants of N was constructed and transfected into COS-7 cells. In indirect immunofluorescence assays with a rabbit anti-BDV N antiserum, wild-type N was located in the nucleus of transfected cells in the absence of other viral constituents. In contrast, mutants lacking the 13 NH2-terminal amino acid residues 1MPPKRRLVDDADA13 in common gave a cytoplasmic localization pattern. Similarly, a mutant with substitution of 4KRR6 by 4NSG6 was retained in the cytoplasm. Furthermore, a nonapeptide, 3PKRRLVDDA11, derived from the NH2-terminal region of N conferred nuclear targeting activity to beta-galactosidase, which normally resides in the cytoplasm. Thus, we have identified the nuclear targeting signal of the BDV N and narrowed it to the NH2-terminal region where 4KRR6 basic amino acid residues are located."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.org/dc/terms/identifier | "doi:10.1006/viro.1998.9049"xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.org/dc/terms/identifier | "doi:10.1006/viro.1998.9049"xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Kobayashi T."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Kobayashi T."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Ikuta K."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Ikuta K."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Kakinuma M."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Kakinuma M."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Kishi M."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Kishi M."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Koda T."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Koda T."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Lai P.K."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Lai P.K."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Shoya Y."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Shoya Y."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Takashima I."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/author | "Takashima I."xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/name | "Virology"xsd:string |
| http://purl.uniprot.org/citations/9527928 | http://purl.uniprot.org/core/name | "Virology"xsd:string |