| http://purl.uniprot.org/citations/9529257 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9529257 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9529257 | http://www.w3.org/2000/01/rdf-schema#comment | "The NFkappaB1 gene encodes two functionally distinct proteins termed p50 and p105. p50 corresponds to the N terminus of p105 and with p65 (RelA) forms the prototypical NF-kappaB transcription factor complex. In contrast, p105 functions as a Rel-specific inhibitor (IKB) and has been proposed to be the precursor of p50. Our studies now demonstrate that p50 is generated by a unique cotranslational processing event involving the 26S proteasome, whereas cotranslational folding of sequences near the C terminus of p50 abrogates proteasome processing and leads to p105 production. These results indicate that p105 is not the precursor of p50 and reveal a novel mechanism of gene regulation that ensures the balanced production and independent function of the p50 and p105 proteins."xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81409-9"xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81409-9"xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/author | "Lin L."xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/author | "Lin L."xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/author | "Greene W.C."xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/author | "Greene W.C."xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/author | "DeMartino G.N."xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/author | "DeMartino G.N."xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/pages | "819-828"xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/pages | "819-828"xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/title | "Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome."xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/title | "Cotranslational biogenesis of NF-kappaB p50 by the 26S proteasome."xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/volume | "92"xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://purl.uniprot.org/core/volume | "92"xsd:string |
| http://purl.uniprot.org/citations/9529257 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9529257 |
| http://purl.uniprot.org/citations/9529257 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9529257 |
| http://purl.uniprot.org/citations/9529257 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9529257 |
| http://purl.uniprot.org/citations/9529257 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9529257 |