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http://purl.uniprot.org/citations/9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9531595http://www.w3.org/2000/01/rdf-schema#comment"To determine the relative in vivo importance of endothelial expressed adhesion molecules to eosinophil rolling, adhesion, and transmigration, we have induced eosinophilic peritonitis using ragweed allergen in P-selectin-deficient, intracellular adhesion molecule-1 (ICAM-1)-deficient and control wild-type mice. Circulating leukocytes visualized by intravital microscopy exhibited reduced rolling and firm adhesion in P-selectin-deficient mice and reduced firm adhesion in ICAM-1-deficient mice. Eosinophils exhibited reduced rolling and firm adhesion to endothelium in P-selectin-deficient mice. Eosinophil recruitment in P-selectin-deficient mice ( approximately 75% inhibition of eosinophil recruitment) and ICAM-1-deficient mice ( approximately 67% inhibition of eosinophil recruitment) was significantly reduced compared with wild-type mice. Eosinophil recruitment was not completely inhibited in P-selectin/ICAM-1 double-mutant mice (eosinophil recruitment inhibited approximately 62%). However, pretreatment of P-selectin/ICAM-1-deficient mice with an anti-vascular cell adhesion molecule (VCAM) antibody induced near complete inhibition of eosinophil recruitment. Overall, these studies show that eosinophil rolling and firm adhesion is significantly reduced in P-selectin-deficient mice and that P-selectin, ICAM-1, and VCAM are important to eosinophil peritoneal recruitment after ragweed challenge."xsd:string
http://purl.uniprot.org/citations/9531595http://purl.uniprot.org/core/author"Sullivan S."xsd:string
http://purl.uniprot.org/citations/9531595http://purl.uniprot.org/core/author"Sriramarao P."xsd:string
http://purl.uniprot.org/citations/9531595http://purl.uniprot.org/core/author"Broide D.H."xsd:string
http://purl.uniprot.org/citations/9531595http://purl.uniprot.org/core/author"Humber D."xsd:string
http://purl.uniprot.org/citations/9531595http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9531595http://purl.uniprot.org/core/name"Blood"xsd:string
http://purl.uniprot.org/citations/9531595http://purl.uniprot.org/core/pages"2847-2856"xsd:string
http://purl.uniprot.org/citations/9531595http://purl.uniprot.org/core/title"Inhibition of eosinophil rolling and recruitment in P-selectin- and intracellular adhesion molecule-1-deficient mice."xsd:string
http://purl.uniprot.org/citations/9531595http://purl.uniprot.org/core/volume"91"xsd:string
http://purl.uniprot.org/citations/9531595http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9531595
http://purl.uniprot.org/citations/9531595http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9531595
http://purl.uniprot.org/uniprot/#_F6TL88-mappedCitation-9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9531595
http://purl.uniprot.org/uniprot/#_P13597-mappedCitation-9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9531595
http://purl.uniprot.org/uniprot/#_Q3THH5-mappedCitation-9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9531595
http://purl.uniprot.org/uniprot/#_Q3U8M7-mappedCitation-9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9531595
http://purl.uniprot.org/uniprot/#_Q4FK06-mappedCitation-9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9531595
http://purl.uniprot.org/uniprot/#_Q922B3-mappedCitation-9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9531595
http://purl.uniprot.org/uniprot/#_Q3UDJ5-mappedCitation-9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9531595
http://purl.uniprot.org/uniprot/#_Q3UE52-mappedCitation-9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9531595
http://purl.uniprot.org/uniprot/#_Q01102-mappedCitation-9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9531595
http://purl.uniprot.org/uniprot/#_Q3TB10-mappedCitation-9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9531595
http://purl.uniprot.org/uniprot/#_Q3TB21-mappedCitation-9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9531595
http://purl.uniprot.org/uniprot/#_Q3UWM1-mappedCitation-9531595http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9531595