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http://purl.uniprot.org/citations/9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9545464http://www.w3.org/2000/01/rdf-schema#comment"Base composition is not uniform across the genome of Drosophila melanogaster. Earlier analyses have suggested that there is variation in composition in D. melanogaster on both a large scale and a much smaller, within-gene, scale. Here we present analyses on 117 genes which have reliable intron/exon boundaries and no known alternative splicing. We detect significant heterogeneity in G+C content among intron segments from the same gene, as well as a significant positive correlation between the intron and the third codon position G+C content within genes. Both of these observations appear to be due, in part, to an overall decline in intron and third codon position G+C content along Drosophila genes with introns. However, there is also evidence of an increase in third codon position G+C content at the start of genes; this is particularly evident in genes without introns. This is consistent with selection acting against preferred codons at the start of genes."xsd:string
http://purl.uniprot.org/citations/9545464http://purl.org/dc/terms/identifier"doi:10.1007/pl00006334"xsd:string
http://purl.uniprot.org/citations/9545464http://purl.uniprot.org/core/author"Eyre-Walker A."xsd:string
http://purl.uniprot.org/citations/9545464http://purl.uniprot.org/core/author"Kliman R.M."xsd:string
http://purl.uniprot.org/citations/9545464http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9545464http://purl.uniprot.org/core/name"J Mol Evol"xsd:string
http://purl.uniprot.org/citations/9545464http://purl.uniprot.org/core/pages"534-541"xsd:string
http://purl.uniprot.org/citations/9545464http://purl.uniprot.org/core/title"Patterns of base composition within the genes of Drosophila melanogaster."xsd:string
http://purl.uniprot.org/citations/9545464http://purl.uniprot.org/core/volume"46"xsd:string
http://purl.uniprot.org/citations/9545464http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9545464
http://purl.uniprot.org/citations/9545464http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9545464
http://purl.uniprot.org/uniprot/#_A0A0B4KFM8-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464
http://purl.uniprot.org/uniprot/#_A0A0B4KHM9-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464
http://purl.uniprot.org/uniprot/#_A0A0B4KEM6-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464
http://purl.uniprot.org/uniprot/#_P10351-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464
http://purl.uniprot.org/uniprot/#_P15348-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464
http://purl.uniprot.org/uniprot/#_P15364-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464
http://purl.uniprot.org/uniprot/#_P15372-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464
http://purl.uniprot.org/uniprot/#_P15425-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464
http://purl.uniprot.org/uniprot/#_P61851-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464
http://purl.uniprot.org/uniprot/#_Q07886-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464
http://purl.uniprot.org/uniprot/#_Q07892-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464
http://purl.uniprot.org/uniprot/#_A0A0B4KEF3-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464
http://purl.uniprot.org/uniprot/#_A0A0B4KGU5-mappedCitation-9545464http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/9545464