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http://purl.uniprot.org/citations/9546393http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9546393http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9546393http://www.w3.org/2000/01/rdf-schema#comment"In the nematode worm C. elegans, individuals with mutations in the spe-9 gene produce spermatozoa with wild-type morphology and motility that cannot fertilize oocytes even after contact between gametes. Therefore, disruption of spe-9 function affects either gamete recognition, adhesion, signaling, and/or fusion. The spe-9 gene encodes a sperm transmembrane protein with an extracellular domain that contains ten epidermal growth factor-like repeats. A common feature of proteins that include epidermal growth factor-like motifs is their involvement in extracellular functions such as adhesive and ligand-receptor interactions. Additionally, the overall structure of the predicted SPE-9 protein is similar to that of ligands for the Notch/LIN-12/GLP-1 family of transmembrane receptors. These results suggest that SPE-9 functions in the specialized cell-cell interactions required for fertilization."xsd:string
http://purl.uniprot.org/citations/9546393http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(00)81147-2"xsd:string
http://purl.uniprot.org/citations/9546393http://purl.org/dc/terms/identifier"doi:10.1016/s0092-8674(00)81147-2"xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/author"Singson A."xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/author"Singson A."xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/author"L'Hernault S.W."xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/author"L'Hernault S.W."xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/author"Mercer K.B."xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/author"Mercer K.B."xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/name"Cell"xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/pages"71-79"xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/pages"71-79"xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/title"The C. elegans spe-9 gene encodes a sperm transmembrane protein that contains EGF-like repeats and is required for fertilization."xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/title"The C. elegans spe-9 gene encodes a sperm transmembrane protein that contains EGF-like repeats and is required for fertilization."xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/volume"93"xsd:string
http://purl.uniprot.org/citations/9546393http://purl.uniprot.org/core/volume"93"xsd:string
http://purl.uniprot.org/citations/9546393http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9546393
http://purl.uniprot.org/citations/9546393http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9546393
http://purl.uniprot.org/citations/9546393http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9546393
http://purl.uniprot.org/citations/9546393http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9546393