| http://purl.uniprot.org/citations/9550719 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9550719 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9550719 | http://www.w3.org/2000/01/rdf-schema#comment | "Tbx-2, Tbx-3, Tbx-4 and Tbx-5 chick genes have been isolated and, like the mouse homologues, are expressed in the limb regions. Tbx-2 and Tbx-3 are expressed in anterior and posterior domains in wings and legs, as well as throughout the flank. Of particular interest, however, are Tbx-5, which is expressed in wing and flank but not leg, and Tbx-4, which is expressed very strongly in leg but not wing. Grafts of leg tissue to wing and wing tissue to leg give rise to toe-like or wing-like digits in wing and leg respectively. Expression of Tbx-4 is stable when leg tissue is grafted to wing, and Tbx-5 expression is stable when wing tissue is grafted to leg. Induction of either extra wings or legs from the flank by applying FGF-2 in different positions alters the expression of Tbx-4 and Tbx-5 in such a way that suggests that the amount of Tbx-4 that is expressed in the limb determines the type that will form. The ectopic limb always displays a limb-like Tbx-3 expression. Thus Tbx-4 and Tbx-5 are strong candidates for encoding 'wingness' and 'legness'."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.125.10.1867"xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.org/dc/terms/identifier | "doi:10.1242/dev.125.10.1867"xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Patel K."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Patel K."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Ryan A."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Ryan A."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Tickle C."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Tickle C."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Tsukui T."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Tsukui T."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Izpisua-Belmonte J.-C."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Izpisua-Belmonte J.-C."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Rodriguez-Esteban C."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Rodriguez-Esteban C."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Altabef M."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Altabef M."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Issac A."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/author | "Issac A."xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/name | "Development"xsd:string |
| http://purl.uniprot.org/citations/9550719 | http://purl.uniprot.org/core/name | "Development"xsd:string |