| http://purl.uniprot.org/citations/9551884 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9551884 | http://www.w3.org/2000/01/rdf-schema#comment | "Antigen presentation by MHC class II (class II) is facilitated by the accessory molecules, invariant chain (Ii) and H2-M. Ii associates with class II during biosynthesis and promotes transport of class II to Ag-loading compartments. One function of H2-M is the removal of Ii fragments from MHC class II. We have previously demonstrated that Ii-deficient mice, unlike class II-deficient mice, are resistant to L. major infection. In the present study, we found that H2-M-deficient (H2-M0) mice were susceptible to progressive infection with L. major. The dispensability of Ii for control of L. major allowed genetic analysis of whether H2-M functions by association with or independently of Ii. In contrast to Ii-deficient (Ii0) mice, Ii0H2-M0 mice were as susceptible to L. major as H2-M0 mice. Thus, H2-M has an essential, Ii-independent function during presentation of microbial pathogens."xsd:string |
| http://purl.uniprot.org/citations/9551884 | http://purl.uniprot.org/core/author | "Brown D.R."xsd:string |
| http://purl.uniprot.org/citations/9551884 | http://purl.uniprot.org/core/author | "Martin W.D."xsd:string |
| http://purl.uniprot.org/citations/9551884 | http://purl.uniprot.org/core/author | "Reiner S.L."xsd:string |
| http://purl.uniprot.org/citations/9551884 | http://purl.uniprot.org/core/author | "Van Kaer L."xsd:string |
| http://purl.uniprot.org/citations/9551884 | http://purl.uniprot.org/core/author | "Swier K."xsd:string |
| http://purl.uniprot.org/citations/9551884 | http://purl.uniprot.org/core/author | "Bird J.J."xsd:string |
| http://purl.uniprot.org/citations/9551884 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9551884 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/9551884 | http://purl.uniprot.org/core/pages | "540-544"xsd:string |
| http://purl.uniprot.org/citations/9551884 | http://purl.uniprot.org/core/title | "A critical, invariant chain-independent role for H2-M in antigen presentation."xsd:string |
| http://purl.uniprot.org/citations/9551884 | http://purl.uniprot.org/core/volume | "160"xsd:string |
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| http://purl.uniprot.org/uniprot/#_A0A494BAR2-mappedCitation-9551884 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551884 |
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| http://purl.uniprot.org/uniprot/#_Q31096-mappedCitation-9551884 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551884 |