| http://purl.uniprot.org/citations/9551890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9551890 | http://www.w3.org/2000/01/rdf-schema#comment | "The ability of TAP1-/-, beta2m-/-, and TAP1/beta2m-/-mice to mount rejection responses against allogeneic, syngeneic, and MHC class I-deficient tumor grafts was examined. The results demonstrate a potent ability of TAP1-/- and beta2m-/- as well as TAP1/beta2m-/-mice to reject allogeneic tumors. In contrast to published data, rejection of syngeneic MHC class I-expressing tumors was also observed. This response was specific for the MHC class I-deficient mice, since wild-type mice did not reject syngeneic MHC class I-positive tumors under identical experimental conditions. The rejection response of syngeneic tumors required preimmunization of the mice and was MHC class I specific at the level of priming as well as at the level of the tumor target. Finally, MHC class I-deficient tumor grafts were accepted in MHC class I-deficient mice while similar grafts were rejected in wild-type mice. In summary, while MHC class I-deficient mice have retained a capacity to reject allogeneic tumors. they have gained an ability to reject syngeneic MHC class I-positive tumors and lost the ability to reject MHC class I-negative tumors. The present results are discussed in relation to the role of MHC class I molecules in selecting functional CD8+ T and NK cell repertoires, and the development of cell-mediated immunity."xsd:string |
| http://purl.uniprot.org/citations/9551890 | http://purl.uniprot.org/core/author | "Andersson M."xsd:string |
| http://purl.uniprot.org/citations/9551890 | http://purl.uniprot.org/core/author | "Ljunggren H.G."xsd:string |
| http://purl.uniprot.org/citations/9551890 | http://purl.uniprot.org/core/author | "Chambers B.J."xsd:string |
| http://purl.uniprot.org/citations/9551890 | http://purl.uniprot.org/core/author | "Van Kaer L."xsd:string |
| http://purl.uniprot.org/citations/9551890 | http://purl.uniprot.org/core/author | "Freland S."xsd:string |
| http://purl.uniprot.org/citations/9551890 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9551890 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/9551890 | http://purl.uniprot.org/core/pages | "572-579"xsd:string |
| http://purl.uniprot.org/citations/9551890 | http://purl.uniprot.org/core/title | "Rejection of allogeneic and syngeneic but not MHC class I-deficient tumor grafts by MHC class I-deficient mice."xsd:string |
| http://purl.uniprot.org/citations/9551890 | http://purl.uniprot.org/core/volume | "160"xsd:string |
| http://purl.uniprot.org/citations/9551890 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9551890 |
| http://purl.uniprot.org/citations/9551890 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9551890 |
| http://purl.uniprot.org/uniprot/#_A0A068BER1-mappedCitation-9551890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551890 |
| http://purl.uniprot.org/uniprot/#_A0A1D8M9B3-mappedCitation-9551890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551890 |
| http://purl.uniprot.org/uniprot/#_A0A494B9G5-mappedCitation-9551890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551890 |
| http://purl.uniprot.org/uniprot/#_A0A494B9U2-mappedCitation-9551890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551890 |
| http://purl.uniprot.org/uniprot/#_P06342-mappedCitation-9551890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551890 |
| http://purl.uniprot.org/uniprot/#_P06343-mappedCitation-9551890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551890 |
| http://purl.uniprot.org/uniprot/#_P06345-mappedCitation-9551890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551890 |
| http://purl.uniprot.org/uniprot/#_P06346-mappedCitation-9551890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551890 |
| http://purl.uniprot.org/uniprot/#_Q31135-mappedCitation-9551890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551890 |
| http://purl.uniprot.org/uniprot/#_Q31184-mappedCitation-9551890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551890 |
| http://purl.uniprot.org/uniprot/#_Q31187-mappedCitation-9551890 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9551890 |