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| http://purl.uniprot.org/citations/9553039 | http://www.w3.org/2000/01/rdf-schema#comment | "Homozygous E2F-5 knockout embryos and mice have been generated. Although embryonic development appeared normal, newborn mice developed nonobstructive hydrocephalus, suggesting excessive cerebrospinal fluid (CSF) production. Although the CSF-producing choroid plexus displayed normal cellular organization, it contained abundant electron-lucent epithelial cells, consistent with excessive CSF secretory activity. Moreover, E2F-5 CNS expression in normal animals was largely confined to the choroid plexus. Cell cycle kinetics were not perturbed in homozygous knockout embryo fibroblasts. Thus, E2F-5 is not essential for cell proliferation. Rather, it affects the secretory behavior of a differentiated neural tissue."xsd:string |
| http://purl.uniprot.org/citations/9553039 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.12.8.1092"xsd:string |
| http://purl.uniprot.org/citations/9553039 | http://purl.uniprot.org/core/author | "Xu Y."xsd:string |
| http://purl.uniprot.org/citations/9553039 | http://purl.uniprot.org/core/author | "Bronson R.T."xsd:string |
| http://purl.uniprot.org/citations/9553039 | http://purl.uniprot.org/core/author | "Livingston D.M."xsd:string |
| http://purl.uniprot.org/citations/9553039 | http://purl.uniprot.org/core/author | "Gaubatz S."xsd:string |
| http://purl.uniprot.org/citations/9553039 | http://purl.uniprot.org/core/author | "Dagnino L."xsd:string |
| http://purl.uniprot.org/citations/9553039 | http://purl.uniprot.org/core/author | "Lindeman G.J."xsd:string |
| http://purl.uniprot.org/citations/9553039 | http://purl.uniprot.org/core/author | "Warren H.B."xsd:string |
| http://purl.uniprot.org/citations/9553039 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9553039 | http://purl.uniprot.org/core/name | "Genes Dev"xsd:string |
| http://purl.uniprot.org/citations/9553039 | http://purl.uniprot.org/core/pages | "1092-1098"xsd:string |
| http://purl.uniprot.org/citations/9553039 | http://purl.uniprot.org/core/title | "A specific, nonproliferative role for E2F-5 in choroid plexus function revealed by gene targeting."xsd:string |
| http://purl.uniprot.org/citations/9553039 | http://purl.uniprot.org/core/volume | "12"xsd:string |
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