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http://purl.uniprot.org/citations/9554855http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9554855http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9554855http://www.w3.org/2000/01/rdf-schema#comment"The ability of bacteria to acquire and disseminate heterologous genes has been a major factor in the development of multiple drug resistance. A gene, intI4, was identified that encodes a previously unknown integrase that is associated with a "gene-VCR" organization (VCRs are Vibrio cholerae repeated sequences), similar to that of the well-characterized antibiotic resistance integrons. The similarity was confirmed by IntI1-mediated recombination of a gene-VCR cassette into a class 1 integron. VCR cassettes are found in a number of Vibrio species including a strain of V. metschnikovii isolated in 1888, suggesting that this mechanism of heterologous gene acquisition predated the antibiotic era."xsd:string
http://purl.uniprot.org/citations/9554855http://purl.org/dc/terms/identifier"doi:10.1126/science.280.5363.605"xsd:string
http://purl.uniprot.org/citations/9554855http://purl.org/dc/terms/identifier"doi:10.1126/science.280.5363.605"xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/author"Davies J."xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/author"Davies J."xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/author"Mazel D."xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/author"Mazel D."xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/author"Dychinco B."xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/author"Dychinco B."xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/author"Webb V.A."xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/author"Webb V.A."xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/name"Science"xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/pages"605-608"xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/pages"605-608"xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/title"A distinctive class of integron in the Vibrio cholerae genome."xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/title"A distinctive class of integron in the Vibrio cholerae genome."xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/volume"280"xsd:string
http://purl.uniprot.org/citations/9554855http://purl.uniprot.org/core/volume"280"xsd:string
http://purl.uniprot.org/citations/9554855http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9554855
http://purl.uniprot.org/citations/9554855http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9554855