http://purl.uniprot.org/citations/9559540 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9559540 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9559540 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Citation |
http://purl.uniprot.org/citations/9559540 | http://www.w3.org/2000/01/rdf-schema#comment | "Saccharomyces cerevisiae mutants lacking Scs7p fail to accumulate the inositolphosphorylceramide (IPC) species. IPC-C, which is the predominant form found in wild-type cells. Instead scs7 mutants accumulate an IPC-B species believed to be unhydroxylated on the amide-linked C26-fatty acid. Elimination of the SCS7 gene suppresses the Ca(2+)-sensitive phenotype of csg1 and csg2 mutants. The CSG1 and CSG2 genes are required for mannosylation of IPC-C and accumulation of IPC-C by the csg mutants renders them Ca(2+)-sensitive. The SCS7 gene encodes a protein that contains both a cytochrome b5-like domain and a domain that resembles the family of cytochrome b5-dependent enzymes that use iron and oxygen to catalyse desaturation or hydroxylation of fatty acids and sterols. Scs7p is therefore likely to be the enzyme that hydroxylates the C26-fatty acid of IPC-C."xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.org/dc/terms/identifier | "doi:10.1002/(sici)1097-0061(19980315)14:4<311::aid-yea220>3.0.co;2-b"xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.org/dc/terms/identifier | "doi:10.1002/(sici)1097-0061(19980315)14:4<311::aid-yea220>3.0.co;2-b"xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.org/dc/terms/identifier | "doi:10.1002/(sici)1097-0061(19980315)14:4<311::aid-yea220>3.0.co;2-b"xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/author | "Beeler T.J."xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/author | "Beeler T.J."xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/author | "Dunn T.M."xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/author | "Dunn T.M."xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/author | "Monaghan E."xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/author | "Monaghan E."xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/author | "Haak D."xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/author | "Haak D."xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/name | "Yeast"xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/name | "Yeast"xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/pages | "311-321"xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/pages | "311-321"xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/title | "Synthesis of monohydroxylated inositolphosphorylceramide (IPC-C) in Saccharomyces cerevisiae requires Scs7p, a protein with both a cytochrome b5-like domain and a hydroxylase/desaturase domain."xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/title | "Synthesis of monohydroxylated inositolphosphorylceramide (IPC-C) in Saccharomyces cerevisiae requires Scs7p, a protein with both a cytochrome b5-like domain and a hydroxylase/desaturase domain."xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/volume | "14"xsd:string |
http://purl.uniprot.org/citations/9559540 | http://purl.uniprot.org/core/volume | "14"xsd:string |