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http://purl.uniprot.org/citations/9581760http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9581760http://www.w3.org/2000/01/rdf-schema#comment"Abl is an axonal tyrosine kinase that has yet to be clearly linked to a receptor; Notch is a receptor for which the signaling pathway remains incompletely understood. We show here that Notch and abl mutations interact synergistically to produce synthetic lethality and defects in axon extension. Surprisingly, we cannot account for these axonal aberrations on the basis of changes in cell identity. We show, moreover, that Notch is present in the growth cones of extending axons, and that the Abl accessory protein Disabled binds to a signaling domain of Notch in vitro. We therefore speculate that Disabled and Abl may play a role in Notch signaling in Drosophila axons, perhaps by binding to the Notch intracellular domain."xsd:string
http://purl.uniprot.org/citations/9581760http://purl.org/dc/terms/identifier"doi:10.1016/s0896-6273(00)81007-7"xsd:string
http://purl.uniprot.org/citations/9581760http://purl.uniprot.org/core/author"Giniger E."xsd:string
http://purl.uniprot.org/citations/9581760http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9581760http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/9581760http://purl.uniprot.org/core/pages"667-681"xsd:string
http://purl.uniprot.org/citations/9581760http://purl.uniprot.org/core/title"A role for Abl in Notch signaling."xsd:string
http://purl.uniprot.org/citations/9581760http://purl.uniprot.org/core/volume"20"xsd:string
http://purl.uniprot.org/citations/9581760http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9581760
http://purl.uniprot.org/citations/9581760http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9581760
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