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http://purl.uniprot.org/citations/9581762http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9581762http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9581762http://www.w3.org/2000/01/rdf-schema#comment"The synaptic protein PSD-95/SAP90 binds to and clusters a variety of membrane proteins via its two N-terminal PDZ domains. We report a novel protein, CRIPT, which is highly conserved from mammals to plants and binds selectively to the third PDZ domain (PDZ3) of PSD-95 via its C terminus. While conforming to the consensus PDZ-binding C-terminal sequence (X-S/T-X-V-COOH), residues at the -1 position and upstream of the last four amino acids of CRIPT determine its specificity for PDZ3. In heterologous cells, CRIPT causes a redistribution of PSD-95 to microtubules. In brain, CRIPT colocalizes with PSD-95 in the postsynaptic density and can be coimmunoprecipitated with PSD-95 and tubulin. These findings suggest that CRIPT may regulate PSD-95 interaction with a tubulin-based cytoskeleton in excitatory synapses."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.org/dc/terms/identifier"doi:10.1016/s0896-6273(00)81009-0"xsd:string
http://purl.uniprot.org/citations/9581762http://purl.org/dc/terms/identifier"doi:10.1016/s0896-6273(00)81009-0"xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Kapoor T.M."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Kapoor T.M."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Sheng M."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Sheng M."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Weinberg R.J."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Weinberg R.J."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Craig A.M."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Craig A.M."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Allison D.W."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Allison D.W."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Niethammer M."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Niethammer M."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Valtschanoff J.G."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/author"Valtschanoff J.G."xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/pages"693-707"xsd:string
http://purl.uniprot.org/citations/9581762http://purl.uniprot.org/core/pages"693-707"xsd:string