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http://purl.uniprot.org/citations/9582303http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9582303http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9582303http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Citation
http://purl.uniprot.org/citations/9582303http://www.w3.org/2000/01/rdf-schema#comment"BLAST analysis of expressed sequence tags (ESTs) using the coding sequence of a human UDP-galactose:beta-N-acetyl-glucosamine beta-1, 3-galactosyltransferase, designated beta3Gal-T1, revealed no ESTs with identical sequences but a large number with similarity. Three different sets of overlapping ESTs with sequence similarities to beta3Gal-T1 were compiled, and complete coding regions of these genes were obtained. Expression of two of these genes in the Baculo virus system showed that one represented a UDP-galactose:beta-N-acetyl-glucosamine beta-1, 3-galactosyltransferase (beta3Gal-T2) with similar kinetic properties as beta3Gal-T1. Another gene represented a UDP-galactose:beta-N-acetyl-galactosamine beta-1, 3-galactosyltransferase (beta3Gal-T4) involved in GM1/GD1 ganglioside synthesis, and this gene was highly similar to a recently reported rat GD1 synthase (Miyazaki, H., Fukumoto, S., Okada, M., Hasegawa, T., and Furukawa, K. (1997) J. Biol. Chem. 272, 24794-24799). Northern analysis of mRNA from human organs with the four homologous cDNA revealed different expression patterns. beta3Gal-T1 mRNA was expressed in brain, beta3Gal-T2 was expressed in brain and heart, and beta3Gal-T3 and -T4 were more widely expressed. The coding regions for each of the four genes were contained in single exons. beta3Gal-T2, -T3, and -T4 were localized to 1q31, 3q25, and 6p21.3, respectively, by EST mapping. The results demonstrate the existence of a family of homologous beta3-galactosyltransferase genes."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.org/dc/terms/identifier"doi:10.1074/jbc.273.21.12770"xsd:string
http://purl.uniprot.org/citations/9582303http://purl.org/dc/terms/identifier"doi:10.1074/jbc.273.21.12770"xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Bennett E.P."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Bennett E.P."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Clausen H."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Clausen H."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Levery S.B."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Levery S.B."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Carneiro F."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Carneiro F."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Almeida R."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Almeida R."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Nomoto M."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Nomoto M."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Schwientek T."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Schwientek T."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Amado M."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Amado M."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Hassan H."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Hassan H."xsd:string
http://purl.uniprot.org/citations/9582303http://purl.uniprot.org/core/author"Hollingsworth M.A."xsd:string