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http://purl.uniprot.org/citations/9585423http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9585423http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9585423http://www.w3.org/2000/01/rdf-schema#comment"Thymus development depends on a complex series of interactions between thymocytes and the stromal component of the organ. To identify regulated genes during this codependent developmental relationship, we have applied an RNA fingerprinting technique to the analysis of thymus expansion and maturation induced in recombinase-deficient mice injected with anti-CD3 antibodies. This approach led us to the identification of a gene encoding a new member of the immunoglobulin superfamily, named epithelial V-like antigen (EVA), which is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. This gene is expressed in the thymus and in several epithelial structures early in embryogenesis. EVA is highly homologous to the myelin protein zero and, in thymus-derived epithelial cell lines, is poorly soluble in nonionic detergents, strongly suggesting an association to the cytoskeleton. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.org/dc/terms/identifier"doi:10.1083/jcb.141.4.1061"xsd:string
http://purl.uniprot.org/citations/9585423http://purl.org/dc/terms/identifier"doi:10.1083/jcb.141.4.1061"xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Mariani M."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Mariani M."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Grassi F."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Grassi F."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Teesalu T."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Teesalu T."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Consalez G.G."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Consalez G.G."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Porcellini S."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Porcellini S."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Panigada M."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Panigada M."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Guttinger M."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Guttinger M."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Merati B."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Merati B."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Sutti F."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/author"Sutti F."xsd:string
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9585423http://purl.uniprot.org/core/date"1998"xsd:gYear