http://purl.uniprot.org/citations/9588953 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9588953 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9588953 | http://www.w3.org/2000/01/rdf-schema#comment | "In the course of systematic investigations on low-molecular-weight compounds from the venom of Crotalidae and Viperidae, we have isolated and characterized at least three bradykinin-potentiating peptides (BPP-II, BPP-III, and BPP-V) from Bothrops neuwiedi venom by gel filtration on Sephadex G-25 M, Sephadex G-10 followed by HPLC. The peptides showed bradykinin-potentiating action on isolated guinea-pig ileum, for which the BPP-V was more active than of BPP-II, and BPP-III, rat arterial blood pressure, and a relevant angiotensin-converting enzyme (ACE) competitive inhibiting activity. The kinetic studies showed a Ki of the order of 9.7 x 10(-3) microM to BPP-II, 7 x 10(-3) microM to BPP-III, and 3.3 x 10(-3) microM to BPP-V. The amino acid sequence of the BPP-III has been determined to be pGlu-Gly-Gly-Trp-Pro-Arg-Pro-Gly-Pro-Glu-Ile-Pro-Pro, and the amino acid compositions of the BPP-II and BPP-V by amino acid analysis were 2Glu-2Gly-1Arg-4Pro-1Ile and 2Glu-2Gly-1Ser-3Pro-2Val-1Ile, with molecular weight of 1372, 1046, and 1078, respectively."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.org/dc/terms/identifier | "doi:10.1023/a:1022545020764"xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.org/dc/terms/identifier | "doi:10.1023/a:1022545020764"xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/author | "Lebrun I."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/author | "Lebrun I."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/author | "Raida M."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/author | "Raida M."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/author | "Schrader M."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/author | "Schrader M."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/author | "Ferreira L.A.F."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/author | "Ferreira L.A.F."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/author | "Galle A."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/author | "Galle A."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/author | "Habermehl G."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/author | "Habermehl G."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/name | "J. Protein Chem."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/name | "J. Protein Chem."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/pages | "285-289"xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/pages | "285-289"xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/title | "Isolation: analysis and properties of three bradykinin-potentiating peptides (BPP-II, BPP-III, and BPP-V) from Bothrops neuwiedi venom."xsd:string |
http://purl.uniprot.org/citations/9588953 | http://purl.uniprot.org/core/title | "Isolation: analysis and properties of three bradykinin-potentiating peptides (BPP-II, BPP-III, and BPP-V) from Bothrops neuwiedi venom."xsd:string |