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http://purl.uniprot.org/citations/9602058http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9602058http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9602058http://www.w3.org/2000/01/rdf-schema#comment"A 15.6 kb genomic clone encompassing the mouse procathepsin E gene was isolated and mapped. Sequencing revealed that the gene consists of nine exons followed by a polyadenylation signal at the 3'-end. The 5'-flanking region appears to be a TATA-less promoter but contains a nucleotide sequence that matches perfectly with the consensus motif of an initiator element [S.T. Smale, Biochim. Biophys. Acta 1351 (1997) 73-88.] to direct accurate initiation of transcription by RNA polymerase. This overlaps the site that was determined for the start of transcription. The absence of features considered typical of TATA-box regulated or housekeeping types of genes is consistent with the low levels of procathepsin E gene expression that are normally observed and might imply a unique sensitivity to or requirement for tissue-specific transcription factors that would account for the sporadic distribution of this aspartic proteinase in cells and tissues. The single copy of the procathepsin E gene was located on chromosome 1, near to that of mouse prorenin, a closely related aspartic proteinase involved in blood pressure regulation."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.org/dc/terms/identifier"doi:10.1016/s0167-4781(98)00028-1"xsd:string
http://purl.uniprot.org/citations/9602058http://purl.org/dc/terms/identifier"doi:10.1016/s0167-4781(98)00028-1"xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/author"Peters C."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/author"Peters C."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/author"Kay J."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/author"Kay J."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/author"Roth W."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/author"Roth W."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/author"Deussing J."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/author"Deussing J."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/author"Tatnell P.J."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/author"Tatnell P.J."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/name"Biochim. Biophys. Acta"xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/name"Biochim. Biophys. Acta"xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/pages"57-66"xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/pages"57-66"xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/title"Mouse procathepsin E gene: molecular organisation and chromosomal localisation."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/title"Mouse procathepsin E gene: molecular organisation and chromosomal localisation."xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/volume"1398"xsd:string
http://purl.uniprot.org/citations/9602058http://purl.uniprot.org/core/volume"1398"xsd:string