http://purl.uniprot.org/citations/9613608 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9613608 | http://www.w3.org/2000/01/rdf-schema#comment | "The Na+-H+ exchanger regulatory factor (NHE-RF) is a cytoplasmic phosphoprotein that was first found to be involved in protein kinase A mediated regulation of ion transport. NHE-RF contains two distinct protein interaction PDZ domains: NHE-RF-PDZ1 and NHE-RF-PDZ2. However, their binding partners are currently unknown. Because PDZ domains usually bind to specific short linear C-terminal sequences, we have carried out affinity selection of random peptides for specific sequences that interact with the NHE-RF PDZ domains and found that NHE-RF-PDZ1 is capable of binding to the CFTR C-terminus. The specific and tight association suggests a potential regulatory role of NHE-RF in cystic fibrosis transmembrane conductance regulator (CFTR) function."xsd:string |
http://purl.uniprot.org/citations/9613608 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(98)00402-5"xsd:string |
http://purl.uniprot.org/citations/9613608 | http://purl.uniprot.org/core/author | "Li M."xsd:string |
http://purl.uniprot.org/citations/9613608 | http://purl.uniprot.org/core/author | "Wang S."xsd:string |
http://purl.uniprot.org/citations/9613608 | http://purl.uniprot.org/core/author | "Guggino W.B."xsd:string |
http://purl.uniprot.org/citations/9613608 | http://purl.uniprot.org/core/author | "Schatz P.J."xsd:string |
http://purl.uniprot.org/citations/9613608 | http://purl.uniprot.org/core/author | "Raab R.W."xsd:string |
http://purl.uniprot.org/citations/9613608 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9613608 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
http://purl.uniprot.org/citations/9613608 | http://purl.uniprot.org/core/pages | "103-108"xsd:string |
http://purl.uniprot.org/citations/9613608 | http://purl.uniprot.org/core/title | "Peptide binding consensus of the NHE-RF-PDZ1 domain matches the C-terminal sequence of cystic fibrosis transmembrane conductance regulator (CFTR)."xsd:string |
http://purl.uniprot.org/citations/9613608 | http://purl.uniprot.org/core/volume | "427"xsd:string |
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