| http://purl.uniprot.org/citations/9656143 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9656143 | http://www.w3.org/2000/01/rdf-schema#comment | "The HIV-1 promoter was used as a model to identify transcription factors involved in LPS-dependent transcription in RAW 264 murine macrophages. Expression plasmids for Ets-2 and PU.1 trans-activated the HIV-1 LTR and recombinant PU.1 and an Ets-2 DNA binding domain/GST fusion protein bound to the 5' kappa B site of the HIV-1 enhancer. Ets-2 mRNA was LPS-inducible in RAW 264 cells and LPS stimulated phosphorylation of threonine 72 residue within the Ets-2 pointed domain. Induction of Ets-2 and other LPS-responsive transcription factors was also observed upon addition of plasmid DNA, which complicates interpretation of transient transfections. The proximal promoter region, containing two Sp1 sites, was also LPS-responsive. We propose that the kappa B elements and the tandem Sp1 sites act as LPS response elements and that kappa B-mediated LPS action involves Ets and rel factors."xsd:string |
| http://purl.uniprot.org/citations/9656143 | http://purl.uniprot.org/core/author | "Hume D.A."xsd:string |
| http://purl.uniprot.org/citations/9656143 | http://purl.uniprot.org/core/author | "Ross I.L."xsd:string |
| http://purl.uniprot.org/citations/9656143 | http://purl.uniprot.org/core/author | "Stacey K.J."xsd:string |
| http://purl.uniprot.org/citations/9656143 | http://purl.uniprot.org/core/author | "Sweet M.J."xsd:string |
| http://purl.uniprot.org/citations/9656143 | http://purl.uniprot.org/core/author | "Ostrowski M.C."xsd:string |
| http://purl.uniprot.org/citations/9656143 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9656143 | http://purl.uniprot.org/core/name | "J Inflamm"xsd:string |
| http://purl.uniprot.org/citations/9656143 | http://purl.uniprot.org/core/pages | "67-83"xsd:string |
| http://purl.uniprot.org/citations/9656143 | http://purl.uniprot.org/core/title | "Involvement of Ets, rel and Sp1-like proteins in lipopolysaccharide-mediated activation of the HIV-1 LTR in macrophages."xsd:string |
| http://purl.uniprot.org/citations/9656143 | http://purl.uniprot.org/core/volume | "48"xsd:string |
| http://purl.uniprot.org/citations/9656143 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9656143 |
| http://purl.uniprot.org/citations/9656143 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9656143 |
| http://purl.uniprot.org/uniprot/#_P15037-mappedCitation-9656143 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9656143 |
| http://purl.uniprot.org/uniprot/P15037 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/9656143 |