http://purl.uniprot.org/citations/9660920 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9660920 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9660920 | http://www.w3.org/2000/01/rdf-schema#comment | "In eukaryotes, tRNAs are synthesized in the nucleus and after several maturation steps exported to the cytoplasm. Here, we identify exportin-t as a specific mediator of tRNA export. It is a RanGTP-binding, importin beta-related factor with predominantly nuclear localization. It shuttles rapidly between nucleus and cytoplasm and interacts with nuclear pore complexes. Exportin-t binds tRNA directly and with high affinity. Its cellular concentration in Xenopus oocytes was found to be rate-limiting for export of all tRNAs tested, as judged by microinjection experiments. RanGTP regulates the substrate-exportin-t interaction such that tRNA can be preferentially bound in the nucleus and released in the cytoplasm."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(00)80036-2"xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(00)80036-2"xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Goerlich D."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Goerlich D."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Izaurralde E."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Izaurralde E."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Hartmann E."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Hartmann E."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Bischoff F.R."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Bischoff F.R."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Kutay U."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Kutay U."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Lipowsky G."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Lipowsky G."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Schwarzmaier P."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/author | "Schwarzmaier P."xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/name | "Mol. Biol. Cell"xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/pages | "359-369"xsd:string |
http://purl.uniprot.org/citations/9660920 | http://purl.uniprot.org/core/pages | "359-369"xsd:string |