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| http://purl.uniprot.org/citations/9678332 | http://www.w3.org/2000/01/rdf-schema#comment | "In essence, the Y* rearrangement in the mouse is a Y chromosome that has been hijacked by a non-Y centromere attached distal to the pseudoautosomal region (PAR). All the Y-unique material is thought to be unaltered, but the recombinatory behaviour of the Y* with the X during male meioisis led to the conclusion that part of the PAR is inverted. In the course of a cross set up to introduce the X-linked mutation Patchy fur (Paf) into XY* males, the Y* chromosome was found to carry the wild type allele of Paf. Paf maps close to the X PAR boundary, so we hypothesised that the inverted region of the Y* PAR originated from an X chromosome that provided not only an inverted copy of proximal PAR, but also an X PAR boundary together with some adjacent X-unique material that included the Paf locus. This hypothesis was validated by Southern analysis using an X PAR boundary probe to show that Y* has an X PAR boundary. Thus the Y* PAR has resulted from an end to end fusion of an X and a Y PAR. Furthermore, it was shown that in conjunction with this PAR-PAR fusion, there has been deletion of both copies of the distally located pseudoautosomal gene Steroid sulfatase (Sts)."xsd:string |
| http://purl.uniprot.org/citations/9678332 | http://purl.org/dc/terms/identifier | "doi:10.1159/000014954"xsd:string |
| http://purl.uniprot.org/citations/9678332 | http://purl.uniprot.org/core/author | "Perry J."xsd:string |
| http://purl.uniprot.org/citations/9678332 | http://purl.uniprot.org/core/author | "Ashworth A."xsd:string |
| http://purl.uniprot.org/citations/9678332 | http://purl.uniprot.org/core/author | "Burgoyne P.S."xsd:string |
| http://purl.uniprot.org/citations/9678332 | http://purl.uniprot.org/core/author | "Mahadevaiah S.K."xsd:string |
| http://purl.uniprot.org/citations/9678332 | http://purl.uniprot.org/core/author | "Palmer S.J."xsd:string |
| http://purl.uniprot.org/citations/9678332 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9678332 | http://purl.uniprot.org/core/name | "Cytogenet Cell Genet"xsd:string |
| http://purl.uniprot.org/citations/9678332 | http://purl.uniprot.org/core/pages | "37-40"xsd:string |
| http://purl.uniprot.org/citations/9678332 | http://purl.uniprot.org/core/title | "The Y* rearrangement in mice: new insights into a perplexing PAR."xsd:string |
| http://purl.uniprot.org/citations/9678332 | http://purl.uniprot.org/core/volume | "80"xsd:string |
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