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http://purl.uniprot.org/citations/9688951http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9688951http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9688951http://www.w3.org/2000/01/rdf-schema#comment"The pathogenic fungus Pneumocystis carinii causes severe pneumonia in patients with impaired immunity, particularly patients with acquired immunodeficiency syndrome. The life cycle of P. carinii is poorly understood, and the inability to continuously culture P. carinii is a major limitation in understanding its cell biology. In fungi homologous to P. carinii, pheromone mating factors signal through a mitogen-activated protein kinase (MAPK) signal transduction cascade, resulting in mitotic cell cycle arrest and entry into a pathway of conjugation, cellular differentiation, and proliferation. Using degenerate PCR and library screening, we have identified a MAPK cDNA in P. carinii that is highly homologous to fungal MAPKs involved in the pheromone mating signal transduction cascade, and we demonstrate MAPK activity in P. carinii lysates with a specific antiserum derived from the translated P. carinii MAPK cDNA sequence."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.org/dc/terms/identifier"doi:10.1152/ajplung.1998.275.1.l193"xsd:string
http://purl.uniprot.org/citations/9688951http://purl.org/dc/terms/identifier"doi:10.1152/ajplung.1998.275.1.l193"xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/author"Leof E.B."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/author"Leof E.B."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/author"Kottom T.J."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/author"Kottom T.J."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/author"Limper A.H."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/author"Limper A.H."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/author"Thomas C.F. Jr."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/author"Thomas C.F. Jr."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/name"Am. J. Physiol."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/name"Am. J. Physiol."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/pages"L193-L199"xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/pages"L193-L199"xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/title"Characterization of a mitogen-activated protein kinase from Pneumocystis carinii."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/title"Characterization of a mitogen-activated protein kinase from Pneumocystis carinii."xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/volume"275"xsd:string
http://purl.uniprot.org/citations/9688951http://purl.uniprot.org/core/volume"275"xsd:string
http://purl.uniprot.org/citations/9688951http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9688951
http://purl.uniprot.org/citations/9688951http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9688951