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http://purl.uniprot.org/citations/9694792http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9694792http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9694792http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Citation
http://purl.uniprot.org/citations/9694792http://www.w3.org/2000/01/rdf-schema#comment"NEDD8 is a ubiquitin (Ub)-like protein. Here we report a novel ubiquitinylation-related pathway for modification by NEDD8. NEDD8 was activated by an E1 (Ub-activating enzyme)-like complex, consisting of APP-BP1 and hUba3 with high respective homologies to the amino- and carboxy-terminal regions of E1 and then linked to hUbc12 (a human homolog of yeast Ub-conjugating enzyme Ubc12p). The major target protein modified by NEDD8 was found to be Hs-cullin-4A (Cul-4A), a member of the family of human cullin/Cdc53 proteins functioning as an essential component of a multifunctional Ub-protein ligase E3 complex that has a critical role in Ub-mediated proteolysis."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.org/dc/terms/identifier"doi:10.1101/gad.12.15.2263"xsd:string
http://purl.uniprot.org/citations/9694792http://purl.org/dc/terms/identifier"doi:10.1101/gad.12.15.2263"xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Tanaka K."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Tanaka K."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Kato S."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Kato S."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Kawashima S."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Kawashima S."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Kawasaki H."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Kawasaki H."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Chiba T."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Chiba T."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Osaka F."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Osaka F."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Aida N."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Aida N."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Saeki M."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/author"Saeki M."xsd:string
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9694792http://purl.uniprot.org/core/name"Genes Dev."xsd:string