| http://purl.uniprot.org/citations/9702198 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9702198 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9702198 | http://www.w3.org/2000/01/rdf-schema#comment | "We have identified a human homolog of the Xenopus forkhead activin signal transducer-1 (xFAST-1). Although significantly different in sequence from its Xenopus counterpart, hFAST-1 shared with xFAST-1 the ability to bind to human Smad2 and activate an activin response element (ARE). The hFAST-1-dependent activation of ARE was completely dependent on endogenous Smad4 and stimulation by a TGF beta-like ligand. The hFAST-1 protein was shown to bind to a novel DNA motif, TGT (G/T) (T/G)ATT, an exact copy of which was present within the ARE. A single copy of this motif could activate a reporter in a TGF beta-dependent fashion but only when an adjacent Smad-binding element was present in the construct. These data suggest that responses to TGF beta family members may be mediated by a DNA-binding complex formed by hFAST-1, hSmad2, and hSmad4."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(00)80120-3"xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.org/dc/terms/identifier | "doi:10.1016/s1097-2765(00)80120-3"xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/author | "Kinzler K.W."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/author | "Kinzler K.W."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/author | "Lengauer C."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/author | "Lengauer C."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/author | "Zhou S."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/author | "Zhou S."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/author | "Vogelstein B."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/author | "Vogelstein B."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/author | "Zawel L."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/author | "Zawel L."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/name | "Mol. Cell"xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/pages | "121-127"xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/pages | "121-127"xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/title | "Characterization of human FAST-1, a TGF beta and activin signal transducer."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/title | "Characterization of human FAST-1, a TGF beta and activin signal transducer."xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/volume | "2"xsd:string |
| http://purl.uniprot.org/citations/9702198 | http://purl.uniprot.org/core/volume | "2"xsd:string |