| http://purl.uniprot.org/citations/9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9705222 | http://www.w3.org/2000/01/rdf-schema#comment | "In the developing Drosophila eye, BarH1 and BarH2, paired homeobox genes expressed in R1/R6 outer photoreceptors and primary pigment cells, are essential for normal eye morphogenesis. Here, we show evidence that BarH1 ectopically expressed under the control of the sevenless enhancer (sev-BarH1) causes two types of cone cell transformation: transformation of anterior/posterior cone cells into outer photoreceptors and transformation of equatorial/polar cone cells into primary pigment cells. sev-BarH1repressed the endogenous expression of the rough homeobox gene in R3/R4 photoreceptors, while the BarH2 homeobox gene was activated by sev-BarH1 in an appreciable fraction of extra outer photoreceptors. In primary pigment cells generated by cone cell transformation, the expression of cut, a homeobox gene specific to cone cells, was completely replaced with that of Bar homeobox genes. Extra outer photoreceptor formation was suppressed and enhanced, respectively, by reducing the activity of Ras/MAPK signaling and by dosage reduction of yan, a negative regulator of the pathway, suggesting interactions between Bar homeobox genes (cell fate determinants) and Ras/MAPK signaling in eye development."xsd:string |
| http://purl.uniprot.org/citations/9705222 | http://purl.org/dc/terms/identifier | "doi:10.1006/dbio.1998.8959"xsd:string |
| http://purl.uniprot.org/citations/9705222 | http://purl.uniprot.org/core/author | "Hayashi T."xsd:string |
| http://purl.uniprot.org/citations/9705222 | http://purl.uniprot.org/core/author | "Kojima T."xsd:string |
| http://purl.uniprot.org/citations/9705222 | http://purl.uniprot.org/core/author | "Saigo K."xsd:string |
| http://purl.uniprot.org/citations/9705222 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9705222 | http://purl.uniprot.org/core/name | "Dev Biol"xsd:string |
| http://purl.uniprot.org/citations/9705222 | http://purl.uniprot.org/core/pages | "131-145"xsd:string |
| http://purl.uniprot.org/citations/9705222 | http://purl.uniprot.org/core/title | "Specification of primary pigment cell and outer photoreceptor fates by BarH1 homeobox gene in the developing Drosophila eye."xsd:string |
| http://purl.uniprot.org/citations/9705222 | http://purl.uniprot.org/core/volume | "200"xsd:string |
| http://purl.uniprot.org/citations/9705222 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9705222 |
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| http://purl.uniprot.org/uniprot/#_Q08012-mappedCitation-9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9705222 |
| http://purl.uniprot.org/uniprot/#_A8Y4W5-mappedCitation-9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9705222 |
| http://purl.uniprot.org/uniprot/#_M9NFP7-mappedCitation-9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9705222 |
| http://purl.uniprot.org/uniprot/#_D1YSG9-mappedCitation-9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9705222 |
| http://purl.uniprot.org/uniprot/#_Q6SAZ5-mappedCitation-9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9705222 |
| http://purl.uniprot.org/uniprot/#_Q6SAZ6-mappedCitation-9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9705222 |
| http://purl.uniprot.org/uniprot/#_Q6SAZ7-mappedCitation-9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9705222 |
| http://purl.uniprot.org/uniprot/#_Q6SAZ8-mappedCitation-9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9705222 |
| http://purl.uniprot.org/uniprot/#_Q6SAZ9-mappedCitation-9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9705222 |
| http://purl.uniprot.org/uniprot/#_Q6SB00-mappedCitation-9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9705222 |
| http://purl.uniprot.org/uniprot/#_Q6SB01-mappedCitation-9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9705222 |
| http://purl.uniprot.org/uniprot/#_Q6SB28-mappedCitation-9705222 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/9705222 |