http://purl.uniprot.org/citations/9708738 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9708738 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/9708738 | http://www.w3.org/2000/01/rdf-schema#comment | "The c-Myc and E2F transcription factors are among the most potent regulators of cell cycle progression in higher eukaryotes. This report describes the isolation of a novel, highly conserved 434 kDa protein, designated TRRAP, which interacts specifically with the c-Myc N terminus and has homology to the ATM/PI3-kinase family. TRRAP also interacts specifically with the E2F-1 transactivation domain. Expression of transdominant mutants of the TRRAP protein or antisense RNA blocks c-Myc- and E1A-mediated oncogenic transformation. These data suggest that TRRAP is an essential cofactor for both the c-Myc and E1A/E2F oncogenic transcription factor pathways."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81479-8"xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0092-8674(00)81479-8"xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/author | "Copeland T.D."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/author | "Copeland T.D."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/author | "Cole M.D."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/author | "Cole M.D."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/author | "Van Buskirk H.A."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/author | "Van Buskirk H.A."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/author | "McMahon S.B."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/author | "McMahon S.B."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/author | "Dugan K.A."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/author | "Dugan K.A."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/pages | "363-374"xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/pages | "363-374"xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/title | "The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/title | "The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins."xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/volume | "94"xsd:string |
http://purl.uniprot.org/citations/9708738 | http://purl.uniprot.org/core/volume | "94"xsd:string |