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http://purl.uniprot.org/citations/9728919http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9728919http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9728919http://www.w3.org/2000/01/rdf-schema#comment"Axon guidance receptors modulate the growth cone cytoskeleton through signaling pathways that are not well understood. Here, we describe the C. elegans unc-115 gene, which encodes a candidate cytoskeletal linker protein that acts in axon guidance. unc-115 mutants have defects in a subset of axons, particularly as the affected axons change environments during outgrowth. The unc-115 gene encodes a putative actin-binding protein that is similar to the human actin-binding protein abLIM/limatin; it has a villin headpiece domain and three LIM domains that could mediate protein interactions. unc-115 is expressed in neurons during their development and is required cell-autonomously in certain neurons for normal axon guidance. We propose that UNC-115 modulates the growth cone actin cytoskeleton in response to signals received by growth cone receptors."xsd:string
http://purl.uniprot.org/citations/9728919http://purl.org/dc/terms/identifier"doi:10.1016/S0896-6273(00)80547-4"xsd:string
http://purl.uniprot.org/citations/9728919http://purl.org/dc/terms/identifier"doi:10.1016/s0896-6273(00)80547-4"xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/author"Bargmann C.I."xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/author"Bargmann C.I."xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/author"Lundquist E.A."xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/author"Lundquist E.A."xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/author"Shaw J.E."xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/author"Shaw J.E."xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/author"Herman R.K."xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/author"Herman R.K."xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/name"Neuron"xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/pages"385-392"xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/pages"385-392"xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/title"UNC-115, a conserved protein with predicted LIM and actin-binding domains, mediates axon guidance in C. elegans."xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/title"UNC-115, a conserved protein with predicted LIM and actin-binding domains, mediates axon guidance in C. elegans."xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/volume"21"xsd:string
http://purl.uniprot.org/citations/9728919http://purl.uniprot.org/core/volume"21"xsd:string
http://purl.uniprot.org/citations/9728919http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9728919
http://purl.uniprot.org/citations/9728919http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9728919