| http://purl.uniprot.org/citations/9736774 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9736774 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9736774 | http://www.w3.org/2000/01/rdf-schema#comment | "The Delta Sxrb interval of the mouse Y chromosome is critical for spermatogenesis and expression of the male-specific minor transplantation antigen H-Y. Several genes have been mapped to this interval and each has a homologue on the X chromosome. Four, Zfy1 , Zfy2 , Ube1y and Dffry , are expressed specifically in the testis and their X homologues are not transcribed from the inactive X chromosome. A further two, Smcy and Uty , are ubiquitously expressed and their X homologues escape X-inactivation. Here we report the identification of another gene from this region of the mouse Y chromosome. It encodes the highly conserved eukaryotic translation initiation factor eIF-2gamma. In the mouse this gene is ubiquitously expressed, has an X chromosome homologue which maps close to Dmd and escapes X-inactivation. The coding regions of the X and Y genes show 86% nucleotide identity and encode putative products with 98% amino acid identity. In humans, the eIF-2gamma structural gene is located on the X chromosome at Xp21 and this also escapes X-inactivation. However, there is no evidence of a Y copy of this gene in humans. We have identified autosomal retroposons of eIF-2gamma in both humans and mice and an additional retroposon on the X chromosome in some mouse strains. Ark blot analysis of eutherian and metatherian genomic DNA indicates that X-Y homologues are present in all species tested except simian primates and kangaroo and that retroposons are common to a wide range of mammals. These results shed light on the evolution of X-Y homologous genes."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.org/dc/terms/identifier | "doi:10.1093/hmg/7.11.1725"xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.org/dc/terms/identifier | "doi:10.1093/hmg/7.11.1725"xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Mattei M.-G."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Mattei M.-G."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Scott D.M."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Scott D.M."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Ehrmann I.E."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Ehrmann I.E."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Affara N.A."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Affara N.A."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Simpson E."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Simpson E."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Brown G.M."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Brown G.M."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Mitchell M.J."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Mitchell M.J."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Brockdorff N."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Brockdorff N."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Ellis P.S."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Ellis P.S."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Mazeyrat S."xsd:string |
| http://purl.uniprot.org/citations/9736774 | http://purl.uniprot.org/core/author | "Mazeyrat S."xsd:string |