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http://purl.uniprot.org/citations/9751741http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9751741http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9751741http://www.w3.org/2000/01/rdf-schema#comment"Ultradian rhythms are widespread phenomena found in various biological organisms. A typical example is the defecation behavior of the nematode Caenorhabditis elegans, which repeats at about 45-sec intervals. To elucidate the mechanism, we studied flr-1 mutants, which show very short defecation cycle periods. The mutations also affect some food-related functions, including growth rate, the expulsion step of defecation behavior, and the regulation of the dauer larva (a nonfeeding, special third-stage larva) formation in the unc-3 (Olf-1/EBF homolog) background. The flr-1 gene encodes a novel ion channel belonging to the DEG/ENaC (C. elegans degenerin and mammalian epithelial sodium channel) superfamily. A flr-1::GFP (green fluorescent protein) fusion gene that can rescue the flr-1 mutant phenotypes is expressed only in the intestine from embryos to adults. These results suggest that FLR-1 may be a component of an intestinal regulatory system that controls the defecation rhythm as well as other functions."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.org/dc/terms/identifier"doi:10.1073/pnas.95.20.11775"xsd:string
http://purl.uniprot.org/citations/9751741http://purl.org/dc/terms/identifier"doi:10.1073/pnas.95.20.11775"xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/author"Katsura I."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/author"Katsura I."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/author"Kondo K."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/author"Kondo K."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/author"Kawakami M."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/author"Kawakami M."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/author"Ishihara T."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/author"Ishihara T."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/author"Take-uchi M."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/author"Amano T."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/author"Amano T."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/author"Take-Uchi M."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/name"Proc. Natl. Acad. Sci. U.S.A."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/name"Proc Natl Acad Sci U S A"xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/pages"11775-11780"xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/pages"11775-11780"xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/title"An ion channel of the degenerin/epithelial sodium channel superfamily controls the defecation rhythm in Caenorhabditis elegans."xsd:string
http://purl.uniprot.org/citations/9751741http://purl.uniprot.org/core/title"An ion channel of the degenerin/epithelial sodium channel superfamily controls the defecation rhythm in Caenorhabditis elegans."xsd:string