| http://purl.uniprot.org/citations/9755858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9755858 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9755858 | http://www.w3.org/2000/01/rdf-schema#comment | "A recombinant GST-Fyn-SH2 domain was used to purify proteins from lysates of pervanadate treated EL4 cells. N-terminal sequencing and molecular cloning of one of the purified polypeptides resulted in the identification of a novel adaptor protein that shares strong structural homology to the recently cloned Fyn-associated adaptor protein SKAP55. This protein was termed SKAP-HOM (SKAP55 homologue). Despite their striking homology, SKAP55 and SKAP-HOM have distinct characteristics. Thus, unlike SKAP55, which is exclusively expressed in T lymphocytes, SKAP-HOM expression is ubiquitous. Furthermore, while SKAP55 is constitutively tyrosine phosphorylated in resting human T cells, SKAP-HOM is expressed as a non-phosphorylated protein in the absence of external stimulus but becomes phosphorylated following T cell activation. In addition, SKAP-HOM does not associate with p59fyn in T cells although it represents a specific substrate for the kinase in COS cells. Finally, we demonstrate that, as previously shown for SKAP55, SKAP-HOM interacts with the recently identified polypeptide SLAP-130."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(98)01040-0"xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.org/dc/terms/identifier | "doi:10.1016/s0014-5793(98)01040-0"xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/author | "Eckerskorn C."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/author | "Eckerskorn C."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/author | "Marie-Cardine A."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/author | "Marie-Cardine A."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/author | "Schraven B."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/author | "Schraven B."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/author | "Verhagen A.M."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/author | "Verhagen A.M."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/pages | "55-60"xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/pages | "55-60"xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/title | "SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/title | "SKAP-HOM, a novel adaptor protein homologous to the FYN-associated protein SKAP55."xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/volume | "435"xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://purl.uniprot.org/core/volume | "435"xsd:string |
| http://purl.uniprot.org/citations/9755858 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9755858 |
| http://purl.uniprot.org/citations/9755858 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9755858 |