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http://purl.uniprot.org/citations/9766967http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9766967http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9766967http://www.w3.org/2000/01/rdf-schema#comment"Casein kinase I (CKI) is a family of widely expressed protein kinases. It is previously shown in mammalian tissues that CKIalpha exists as two or three alternatively spliced isoforms (Rowles et al.,1991; Zhang et al., 1996; Kuret et al., 1997). We now report that four alternatively spliced isoforms of CKIalpha are expressed in many chicken cells and tissues. A partial cDNA clone was isolated from a chicken brain library, using a probe derived from a bovine CKIalpha cDNA. The translated sequence of this clone was 100% identical to the bovine homolog containing the 'L' insert, with the addition of 12 amino acids just before the C terminus that had previously been reported in human and Xenopus CKIalpa. After completing the missing portion of the coding sequence by 5' RACE (rapid amplification of cDNA ends), full-length cDNA was PCR amplified from chicken brain cDNA, yielding four different products. These were cloned and sequenced and found to correspond to the four CKIalpha isoforms: CKIalpha, CKIalphaL, CKIalphaS and CKILalphaLS, where 'S' is the insert consisting of the 12 human/Xenopus C-terminal amino acids. Using reverse transcription and polymerase chain reaction (Rt-PCR), it was shown that the four isoforms are all expressed in neurons, fibroblasts and several tissues. This represents the first demonstration that four splice variants exist and are all expressed in a single type of cell."xsd:string
http://purl.uniprot.org/citations/9766967http://purl.org/dc/terms/identifier"doi:10.1016/s0378-1119(98)00291-1"xsd:string
http://purl.uniprot.org/citations/9766967http://purl.org/dc/terms/identifier"doi:10.1016/s0378-1119(98)00291-1"xsd:string
http://purl.uniprot.org/citations/9766967http://purl.org/dc/terms/identifier"doi:10.1016/S0378-1119(98)00291-1"xsd:string
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/author"Bennett G.S."xsd:string
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/author"Bennett G.S."xsd:string
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/author"Green C.L."xsd:string
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/author"Green C.L."xsd:string
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/pages"189-195"xsd:string
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/pages"189-195"xsd:string
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/title"Identification of four alternatively spliced isoforms of chicken casein kinase I alpha that are all expressed in diverse cell types."xsd:string
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/title"Identification of four alternatively spliced isoforms of chicken casein kinase I alpha that are all expressed in diverse cell types."xsd:string
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/volume"216"xsd:string
http://purl.uniprot.org/citations/9766967http://purl.uniprot.org/core/volume"216"xsd:string
http://purl.uniprot.org/citations/9766967http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9766967
http://purl.uniprot.org/citations/9766967http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/9766967
http://purl.uniprot.org/citations/9766967http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9766967
http://purl.uniprot.org/citations/9766967http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/9766967
http://purl.uniprot.org/uniprot/P67962http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/9766967