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http://purl.uniprot.org/citations/9767135http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9767135http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/9767135http://www.w3.org/2000/01/rdf-schema#comment"EMMPRIN (extracellular matrix metalloproteinase inducer) also known as CD147 and basigin, is a member of the immunoglobulin family that is present on the surface of tumor cells and stimulates nearby fibroblasts to synthesize matrix metalloproteinases. Using our EMMPRIN cDNA, we have isolated a cosmid clone that contains the human EMMPRIN gene. S1 analysis with a fragment of the gene clone and primer extension of the mRNA was performed to determine the transcription start site. PCR and sequence analysis have defined the exon/intron organization of the gene and show that it is highly conserved with the mouse EMMPRIN/basigin gene. About 950 bases of the 5'-flanking region were examined for transcription factor consensus binding sites, locating three SP1 sites and two AP2 sites. The transcription start site was found to be located in a CpG island. Elements in the proximal promoter region were conserved in the human and mouse genes."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.org/dc/terms/identifier"doi:10.1016/s0378-1119(98)00400-4"xsd:string
http://purl.uniprot.org/citations/9767135http://purl.org/dc/terms/identifier"doi:10.1016/s0378-1119(98)00400-4"xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/author"Guo H."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/author"Guo H."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/author"Biswas C."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/author"Biswas C."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/author"Gordon M.K."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/author"Gordon M.K."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/author"Jensen T.C."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/author"Jensen T.C."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/author"Majmudar G."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/author"Majmudar G."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/author"Toole B.P."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/author"Toole B.P."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/date"1998"xsd:gYear
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/name"Gene"xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/pages"99-108"xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/pages"99-108"xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/title"Characterization of the gene for human EMMPRIN, a tumor cell surface inducer of matrix metalloproteinases."xsd:string
http://purl.uniprot.org/citations/9767135http://purl.uniprot.org/core/title"Characterization of the gene for human EMMPRIN, a tumor cell surface inducer of matrix metalloproteinases."xsd:string