| http://purl.uniprot.org/citations/9767710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9767710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/9767710 | http://www.w3.org/2000/01/rdf-schema#comment | "The organization of the clusters of genes encoding proteins of the botulinum neurotoxin (BoNT) progenitor complex was elucidated in a strain of Clostridium botulinum producing type B and F neurotoxins. With PCR and sequencing strategies, the type B BoNT-gene cluster was found to be composed of genes encoding BoNT/B, nontoxic nonhemagglutinin component (NTNH), P-21, and the hemagglutinins HA-33, HA-17, and HA-70, whereas the type F BoNT-gene cluster has genes encoding BoNT/F, NTNH, P-47, and P-21. Comparative sequence analysis showed that BoNT/F in type BF strain 3281 shares highest homology with BoNT/F of non-proteolytic (group II) C. botulinum whereas NTNH and P-21 in the type F cluster of strain 3281 are more similar to the corresponding proteins in proteolytic (group I) type F C. botulinum. These findings indicate diverse evolutionary origins for genes encoding BoNT/F and its associated non-toxic proteins, although the genes are contiguous. By contrast, sequence comparisons indicate that genes encoding BoNT/B and associated non-toxic proteins in strain 3281 possess a similar evolutionary origin. It was demonstrated that the genes present in the BoNT/B gene cluster of this type BF strain show exceptionally high homology with the equivalent genes in the silent BoNT/B gene cluster of C. botulinum type A(B), possibly indicating their common ancestry."xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.org/dc/terms/identifier | "doi:10.1007/s002849900384"xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.org/dc/terms/identifier | "doi:10.1007/s002849900384"xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/author | "East A.K."xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/author | "East A.K."xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/author | "Collins M.D."xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/author | "Collins M.D."xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/author | "Santos-Buelga J."xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/author | "Santos-Buelga J.A."xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/date | "1998"xsd:gYear |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/name | "Curr. Microbiol."xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/name | "Curr Microbiol"xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/pages | "312-318"xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/pages | "312-318"xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/title | "Characterization of the genes encoding the botulinum neurotoxin complex in a strain of Clostridium botulinum producing type B and F neurotoxins."xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/title | "Characterization of the genes encoding the botulinum neurotoxin complex in a strain of Clostridium botulinum producing type B and F neurotoxins."xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/volume | "37"xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://purl.uniprot.org/core/volume | "37"xsd:string |
| http://purl.uniprot.org/citations/9767710 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9767710 |
| http://purl.uniprot.org/citations/9767710 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/9767710 |
| http://purl.uniprot.org/citations/9767710 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9767710 |
| http://purl.uniprot.org/citations/9767710 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/9767710 |